Published: 2020-02-26

T cell/histiocyte rich large B cell lymphoma of ascending colon: a rare entity

Vinita Agrawal, Mithlesh Bhargav, Supriya Sharma, Vaibhav Raj Gopal


Colonic T cell/histiocyte rich large B cell lymphoma (THRLBCL) is a very unusual occurrence never described before. A 41-year anaemic male presented with loss of weight and appetite for 7 months and fever with Malena for 1 month. Abdominal examination revealed a 4×6 cm retroperitoneal lump in the right iliac fossa. Radiological investigations (USG and CECT whole abdomen) reported an asymmetrical ill-defined growth in ascending colon and caecum with loco-regional lymphadenopathy. Surgical exploration revealed an ascending colon mass with retroperitoneal lymphadenopathy. Right hemi-colectomy with end ileostomy was done and specimen was sent for histopathology which diagnosed it to be a case of THRLBCL of colon. Patient was followed up after 2 weeks and was planned for chemotherapy.


Colonic epithelial malignancy, Diffuse large B-cell lymphoma, Lenalidomide, Nodular lymphocyte predominant Hodgkin lymphoma, T cell/histiocyte rich large B cell

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