Isolated giant plexiform neurofibroma of lower back: a rare case presentation


  • Devansh Mishra Department of General Surgery, NKP Salve Institute of Medical Sciences, Nagpur, Maharashtra, India
  • Nitin Wasnik Department of General Surgery, NKP Salve Institute of Medical Sciences, Nagpur, Maharashtra, India
  • Priyanka Sakarkar Department of General Surgery, NKP Salve Institute of Medical Sciences, Nagpur, Maharashtra, India



Giant plexiform neurofibroma, Back, Neurofibromatosis type 1


Plexiform neurofibroma is a rare benign tumor of the peripheral tissue cells that develops in the perineurium that is often considered pathognomonic of neurofibromatosis type 1 (NF1 or von Recklinghausen disease). They occur most frequently in the craniomaxillofacial region, rarely on back and extremities. They are extremely vascular and there is 15-20% potential for malignant transformation. A 35-year-old married female presented with painless swelling in left lower back that began at around 8 years of age. The swelling gradually increased in size. The patient reported embarrassment over the disfigurement caused by the mass. Her medical history was unremarkable and none of the relatives was known to be affected. Surgical resection of the swelling with primary closure was done. Histopathology findings were consistent with neurofibromatosis. Hereby reporting a rare case of isolated plexiform neurofibroma of lower back which was surgically cured as a perusal of rare entity. We also try to emphasize on the need of sprightful clinical diagnosis with multidisciplinary approach in the management of these type of tumors. Finally, we insist on the need of a long term clinical and radiological follow-up of these patients to assess  post resection recurrence or malignant transformation.

Author Biography

Devansh Mishra, Department of General Surgery, NKP Salve Institute of Medical Sciences, Nagpur, Maharashtra, India

Junior Resident, Department of surgery, Lata Mangeshkar Hospital, Digdoh Hills, Nagpur


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