A comparative prospective study of preoperative antibiotic prophylaxis in the prevention of surgical site infections


  • Suresh Karlatti Department of Surgery, Belgaum Institute of Medical Sciences, Belgaum, Karnataka, India
  • I. B. Havannavar Department of Surgery, Belgaum Institute of Medical Sciences, Belgaum, Karnataka, India




Clean, Clean contaminated, Prophylactic antibiotic, Risk factors, Surgical site infection


Background: Most common cause of post-operative morbidity is surgical site infection (SSI) in planned cases accounting nearly 65% to 80% of all cases in our population. Prior to the use of prophylactic antibiotic, the incidence of surgical site infection was more, which has been drastically reduced the incidence of surgical site infection. This study was conducted to know the need for antibiotic prophylaxis in clean, clean-contaminated surgical wounds and whether prophylactic antibiotic is itself sufficient to minimize surgical site infection.

Methods: 300 patients admitted during January 2011 to December 2012 in District hospital Belgaum, attached to Belgaum Institute of Medical Sciences were selected for our study and were subjected for clean or clean contaminated surgeries done under meticulous surgical technique.

Results: Our study showed that there is no need for prophylactic antibiotics in cases of clean surgeries. We recommend antibiotic prophylaxis in clean contaminated cases. The incidence of surgical site infection depends on various factors like old age (21.91%), anaemia (23.97%), Diabetes mellitus (20.54%) and prolonged duration of surgery more than 2 hours (14.38%).  

Conclusions: From this study we can conclude that, in cases of clean surgeries there is no need for prophylactic antibiotics, as there is no statistical significance, whereas in clean contaminated cases antibiotic prophylaxis is recommended as it reduces SSI statistically significant.


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Original Research Articles