Diagnostic utility of fine needle aspiration cytology in salivary gland lesions: a teaching institutional experience

Authors

  • Shilpa M. Shetty Department of Pathology, Shimoga institute of Medical Sciences, Shimoga, Karnataka, India
  • Kusuma K. N. Department of Pathology, Adichunchanagiri institute of Medical Sciences, B G Nagar, Mandya, Karnataka, India

DOI:

https://doi.org/10.18203/2349-2902.isj20195103

Keywords:

Parotid, FNAC, Pleomorphic adenoma, Histopathology, Diagnostic accuracy

Abstract

Background: Fine needle aspiration cytology (FNAC) is being widely used for pre-operative diagnosis of salivary gland lesions. It is a simple, cost effective and safe procedure that provides valuable information for planning appropriate management. The aim was to study cytohistopathological correlation of salivary gland lesions; to examine sensitivity, specificity and diagnostic accuracy of fine needle aspiration cytology of salivary gland lesions.

Methods: A 4 year 8 months study was conducted from January 2015 to August 2019. Salivary gland lesion FNAC performed in the Department of Pathology, SIMS, Shimoga who were followed up with corresponding biopsy specimen were included in the study.

Results: Total of 42 cases was included in the study. Pleomorphic adenoma was the commonest lesion encountered. The overall sensitivity, specificity, diagnostic accuracy, positive predictive value and negative predictive value was 50%, 97.22%, 90.47%, 75% and 92.10%. Diagnostic pit falls occurred because of sampling error and overlapping morphological features.

Conclusions: Fine needle aspiration (FNA) though poses diagnostic dilemma in some cases, it still forms an easy and less invasive procedure that can assess therapeutic management of salivary gland lesions.

References

Ali NS, Akhtar S, Junaid M, Awan S, Aftab K. Diagnostic accuracy of fine needle aspiration cytology in Parotid lesions. Int Scholarly Res Net. 2011:721525:1-5.

Naz S, Hashmi A A, Khurshid A, Faridi N, Edhi M M, Kamal A, Khan M. Diagnostic role of fine needle aspiration cytology (FNAC) in the evaluation of salivary gland swelling: an institutional experience. BMC Res Notes. 2015;8:1-5.

Zbaren P, Nuyens M, Loosli H, Stauffer E. Diagnostic accuracy of fine needle aspiration cytology and frozen section in primary parotid carcinoma. Cancer. 2004;100:1876-83.

Choudhury S, Mishra B. A study on cytohistopathologic correlation in diagnosis of salivary gland lesions. J Evid Based Med Health. 2016;3(87):4733-6.

Gupta R, Dewan D, Kumar D, Suri J. Fine needle aspiration cytology (FNAC) of salivary gland lesions with histopathological correlation in a district hospital of Jammu region. Indian J Pathol Oncol. 2016;3(1):32-7.

Tessy PJ, Jayalekshmy PS, Cicy PJ, Poothiode U. Fine needle aspiration cytology of salivary gland lesions with histopathological correlation - A two year study. Int J Healthcare Biomed Res. 2015;3(4):91-9.

Omhare A, Singh SK, Nigam JS, Sharma A. Cytohistopathological study of salivary gland lesions in Bundelkhand region, Uttar Pradesh, India. Pathol Res Int. 2014;804265:1-5.

Saldanha C, Fernandes H, Fazalbhoy Z, Jayaprakash CS, Sumanth D, Kini R. Diagnostic accuracy and pitfalls in Fine needle aspiration cytology of Salivary gland lesions. Ann Pathol Lab Med. 2017;4(3):274-8.

Todase V, Panchonia A, Kulkarni CV, Mehar R, Shinde P, Likhar K, et al. Cytopathological study of salivary gland lesion in patients at a tertiary care centre, Indore: a one - year study. Int J Res Med Sci. 2017;5(6):2406-11.

Kakoty S, Baruah T D, Ganesh Babu C P. FNAC and histopathological correlation of salivary gland lesions: an observational study. Int Surg J. 2017;4(7):2148-52.

Arul P, Akshatha C, Masilamani S, Jonathan S. Diagnosis of Salivary gland lesions by fine needle aspiration cytology and its histopathological correlation in a tertiary care centre in Southern India. J Clin Diagnos Res. 2015;9(6):7-10.

Vishwanathan K, Sung S, Scognamiglio T, Yang GC, Siddiqui MT, Rao RA. The role of the Milan system for reporting salivary gland cytopathology: A 5 year institutional experience. Cancer Cytopathol. 2018;126(8):541-51.

Zerpa VZ, Gonzales MT, Porras GA, Acuna MM, Ferriol EE, Galofre JD. Diagnostic accuracy of Fine needle aspiration cytology in parotid tumors. Acta Otorrinolaringol. 2014;65(3):157-61.

Eveson JW, Auclair P, Gnepp DR, El-Naggar AK. Tumours of the salivary glands: Introduction. In: Barnes L, Eveson JW, Reichart P, Sidransky D. World health organization Classification of tumors - Pathology and genetics, Head and neck tumors. Lyon: IARC; 2005: 212-214.

McHugh JB. Major and minor salivary glands. In: Goldblum JR, Lamps LW, McKenney JK, Myer JL. Rosai and Ackerman’s Surgical Pathology. Volume 1, Edition 11th. Philadelphia: Elsevier; 2018: 235-238.

Mills SE. Salivary glands. In: Mills SE, Greenson JK, Hornick JL, Longacre TA, Reuter VE. Sternberg’s Diagnostic surgical pathology. Edition 6th. Philadelphia: Wolters Kluwer; 2015: 906-912.

Young JA, Warfield AT. The salivary glands. In: Gray W, McKee GT. Diagnostic cytopathology. Edition 2nd. Philadelphia: Elsevier; 2003: 305-306.

Klijanienko J. Head and neck; salivary glands. In: Orell SR, Sterett GF, Whitaker D. Fine needle aspiration cytology. Edition 4th. India: Churchill Livingstone; 2005: 42-44.

Verma S. Fine needle aspiration cytology of salivary gland lesions: study in a tertiary care hospital of North Bihar. Int J Res Med Sci. 2016;4(9):3869-72.

Bobati SS, Patil B V, Dombale V D. Histopathological study of salivary gland tumors. J Oral Maxillofacial Pathol. 2017;21(1):46-50.

Sushma HM, Shashidhar MR, Meghashree V, Pai MR. Fine needle aspiration of salivary gland lesions - diagnostic pitfalls. J Evol Med Dent Sci. 2017;6(8):600-4.

Upasana P, Ina S, Hansa G. A cytological and histological comparative study of salivary gland lesions at tertiary health care centre. Int J Biomed Adv Res. 2015;6(6):470-4.

Downloads

Published

2019-10-24

Issue

Section

Original Research Articles