Clinical outcomes following esophagectomy for benign esophageal diseases: a single center experience


  • Jeya Sudhahar Jesudason Department of Surgery, Velammal Medical College and Hospital Madurai, Tamil Nadu, India
  • Karpagavel Chandrabose Department of Surgery, Velammal Medical College and Hospital Madurai, Tamil Nadu, India



Benign esophageal disease, Esophagectomy, Post-operative complications


Background: Surgery is the treatment option for wide range of benign esophageal diseases. But there are very few studies on Indian population, documenting the profile and clinical outcome of esophageal disease treated by surgical intervention. Hence author undertook a study to determine the clinical outcomes following esophagectomy for benign esophageal diseases.

Methods: The current study was a prospective observational study, conducted in Velammal Medical College, Madurai. Data collection was done for 6 years from January 2012 to December 2017. Patients diagnosed with benign esophageal diseases were enrolled. The surgical procedures performed and outcomes were documented. Mean and standard deviation were used to summarize numeric variables, number and percentage were used to summarize categorical variables.

Results: A total of 20 cases were included, with 11 men and 9 women. The mean age was 42.6±8.3 years. Dysphagia (90%) was the most common presentation, followed by heart burn (58%), regurgitation (40%) and chest pain (25%). Boerhaave syndrome (25%) was the most common diagnosis followed by foreign body perforation in 2(10%) patients. Corrosive stricture, peptic stricture, perforation following pneumatic dilatation and end stage achalasia were present in 2(10%) patients each. Jejunostomy and pyloroplasty were the procedure done in all cases. Stomach was the conduit used in 90% of patients. The conduit placement was done in the posterior mediastinum. The duration of the hospital stay ranged from 10 to 35 days. Mortality rate was 10%. Pulmonary morbidity (40%) was the most common post-operative complication, followed by wound infection (20%). Anastomotic stricture occurred among 30% of subjects.

Conclusions: There is a high probability of occurrence complications following esophagectomy for benign disease. Clinicians must be aware of incidence of various complications, to be able to minimize and manage them effectively.



Patil AS, Gulavani NV, Dharmadhikari NP, Polavarapu KC, Sharma SS, Mistry RC. Perioperative complications of esophagectomy: Postneoadjuvant treatment versus primary surgery-Our experience and review of literature. Ind J Cancer. 2017;54(2):439.

Cooke DT, Calhoun RF, Kuderer V, David EA. A defined esophagectomy perioperative clinical care process can improve outcomes and costs. Am Surg. 2017;83(1):103-11.

Zhao H, Zhou Y, Feng J, Wang W, Mei Y. Literature analysis of the treatment of benign esophageal disease with stent. Indi J Surg. 2016;78(1):6-13.

Gockel I, Rabe SM, Niebisch S. Before and after Esophageal Surgery: Which Information Is Needed from the Functional Laboratory. Visc Medi.2018;34(2):116-21.

Law S, Wong KH, Kwok KF, Chu KM, Wong J. Predictive factors for postoperative pulmonary complications and mortality after esophagectomy for cancer. Annal Surg. 2004;240(5):791.

Raymond DP, Friedberg JS, Chen W. Complications of esophageal resection. Up to date. 2017.

D'Journo XB, Thomas PA. Current management of esophageal cancer. J Thorac Dis. 2014;6(2):253-64.

Togo S, Li J, Ligang L, Wei X, Tiechang P, Chen T, et al. Complications and mortality after esophagectomy for esophageal carcinoma: risk factor analysis in a series of 378 patients. Chir Thorac Cardio Vasc. 2010;14:25-8.

Watson TJ, DeMeester TR, Kauer WK, Peters JH, Hagen JA. Esophageal replacement for end-stage benign esophageal disease. J thora Cardior Surg. 1998;115(6):1241-9.

Orringer MB, Marshall B, Iannettoni. Transhiatal esophagectomy for treatment of benign and malignant esophageal disease. World J Surg. 2001;25(2):196-203.

Orringer MB, Marshall B, Chang AC, Lee J, Pickens A, Lau CL. Two thousand transhiatal esophagectomies: changing trends, lessons learned. Annal Surg. 2007;246(3):363.

Schieman C, Wigle DA, Deschamps C, Nichols Iii FC, Cassivi SD, Shen KR, et al. Patterns of operative mortality following esophagectomy. Dis Esophag. 2012;25(7):645-51.






Original Research Articles