Comparison between histopathology and fine needle aspiration cytology in the case of breast lumps
DOI:
https://doi.org/10.18203/2349-2902.isj20195129Keywords:
Benign breast disease, Carcinoma breast, Fibroadenoma, Fine needle aspiration cytology, Histopathology, PhyllodesAbstract
Background: Breast lump is one of the common pathologies seen in surgical practice. Hence it is of importance to have a reliable diagnostic method to distinguish between benign and malignant lumps. Aim of this study was to bring out fine needle aspiration cytology (FNAC) as a rapid, inexpensive, accurate and least invasive diagnostic method for this purpose.
Methods: A prospective study conducted between December 2017 to November 2018 on all 30 patients admitted at Rajarajeswari Medical College and Hospital with breast lumps. Patients were subjected to clinical examination FNAC and Histopathology.
Results: Clinically 64% were categorized as benign lumps and 36% malignant. On FNAC 64% were fibroadenoma, 30% suggestive of malignancy and 6% suspicious of malignancy. On Histopathology 60% were fibroadenoma, 33% turned out to be carcinoma and 7% benign phyllodes. 4% of benign lesions on FNAC turned out malignant on histopathology.
Conclusions: Although son mammography is the conventional approach with a sensitivity of 76.5% and specificity of 90.48%, in this study FNAC was found to have sensitivity of 96.6% and specificity of 100% and can be a reliable tool for early diagnosis in the case of breast lumps.
References
American Cancer Society: Cancer Facts and Figures 2019.
Jindal U, Singh K, Kochhar A. Fine needle aspiration cytology of breast lumps with histopathological correlation: A Four Year and eight-month study from rural India. Internet J Pathol. 2012;13(3):20-4.
Ukah CO, Oluwasola OA. The clinical effectiveness of fine needle aspiration biopsy in patients with palpable breast lesions seen at the University College Hospital, Ibadan, Nigeria: A 10-year retrospective study. J Cytol Ind Acad Cytol. 2011;28(3):111.
Tham TM, Iyengar KR, Taib NA, Yip CH. Fine needle aspiration biopsy, core needle biopsy or excision biopsy to diagnose breast cancer-which is the ideal method?. Asia Paci J Cancer Pre. 2009;10(1):155-8.
Bukhari MH, Arshad M, Jamal S. Use of Fine Needle Aspiration in the Evaluation of Breast lumps Pathology. Res Int. 2011.
Ibikunle DE, Omotayo JA, Ariyibi OO. Fine needle aspiration cytology of breast lumps with histopathologic co relation in Owo,Ondo State,Nigeria:A five year review. Ghana Med J. 2017:51(1):1-5.
Hirachand S, Lakhey M, Akthar J, Ghimire R, Dhakhwan R. Comparison of FNAC and open biopsy in palpable breast lumps. Health renaissance. 2010;7(1):9–12.
Kumar PSK, Mahesh GS. Clinical Profile and Correlation between FNAC and Histopathology of Breast Lumps in a Teaching Hospital. Glob J Med Res. 2014;14:2.