Peptic perforation in paediatric case of dengue: rare presentation


  • Mahalaxmi Pillai Department of Surgery, Gujarat Adani Institute of Medical Science, Bhuj, Gujarat, India
  • Gyaneshwar Rao Department of Surgery, Gujarat Adani Institute of Medical Science, Bhuj, Gujarat, India



Dengue fever, Gastrointestinal symptoms, Headache, Perforation


Dengue fever is a common disease in tropical and subtropical regions and is characterized by fever, headache, and joint and muscle pain. Occasionally, patients develop abdominal and gastrointestinal symptoms. Gastrointestinal manifestations are increasingly being identified in severe dengue infection. Gastric perforation is very rare manifestation in dengue infection. Here we report a case of a 12 year old female who was diagnosed with dengue fever with perforative peritonitis due to prepyloric perforation with no prior symptoms of gastric ulcer.


Gubler DJ, Clark GG. Dengue/dengue hemorrhagic fever: the emergence of a global health problem. Emerg Infect Dis. 1995;1:55–7.

Gubler DJ, Kuno G, Sather GE, Velez M, Oliver A. Mosquito cell cultures and specific monoclonal antibodies in surveillance for dengue virus. Am J Trop Med Hyg. 1984;33:158–65.

Gulati S, Maheshwari A. Atypical manifestations of dengue. Trop Med Int Health. 2007;12:1087–95.

Narayana M, Aravind MA, Thilothammal N, Prema R, Sargunam CSR, Ramamurthy N. Dengue fever epidemic in Chennai: a study of clinical profile and outcome. Indian Pediatr. 2002;39:1027-33.

Wiwanitkit V. Dengue hemorrhagic fever presenting as acute abdomen. Sultan Qabous Univ Med J. 2012;12(1):129-30.

De Souza LJ, Carneiro HG, Souto Filho JT, Ferreira de Souza T, Azevedo Côrtes V, Neto CG, et al. Hepatitis in dengue shock syndrome. Braz J Infect Dis. 2002;6(6):322-7.

Alam SM, Bhuiya MMR, Islam A, Paul S. Perforated gas containing hollow viscous: a study in a hospital, Bangladesh. Orion. 2002;12:1–7.

Mandhane N, Ansari S, Shaikh T, Deolekar S, Mahadik A, Karandikar S. Dengue presenting as gastric perforation: first case reported till date. Int J Res Med Sci. 2015;3:2139–40.

Jain AC, Viswanath S. Multiple jejunal perforations in dengue. Int J Adv Med. 2014;1:153–4.

Desai G, Gupta S, Ali S, Aggarwal L, Thomas S. Appendicular perforation in dengue fever: our experience. Asian Pac J Trop Dis. 2014;4(2):571–2.

Vejchapipat P, Theamboonlers A, Chongsrisawat V, Poovorawan Y. An evidence of intestinal mucosal injury in dengue infection. Southeast Asian J Trop Med Public Health. 2006;37(1):79–82.






Case Reports