A comparative evaluation of analgesic effects of using intravenous paracetamol versus intravenous diclofenac post-operatively                             in laparoscopic cholecystectomy patients in SMIH, department of surgery, Dehradun

Anurag Bijalwan; Pradeep Singhal; Syed Altamash

doi:10.18203/2349-2902.isj20191896

Authors

Anurag Bijalwan Department of General Surgery, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand
Pradeep Singhal Department of General Surgery, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand
Syed Altamash Department of General Surgery, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand

DOI:

https://doi.org/10.18203/2349-2902.isj20191896

Keywords:

Lap cholecystectomy, Analgesia, Paracetamol, Diclofenac

Abstract

Background: Post-operative adequate analgesia plays an important role in early mobilization, short hospital stay and patient satisfaction in laparoscopic cholecystectomy. The use of opioids for providing postoperative analgesia has been marked by side effects like vomiting, nausea, sedation, respiratory distress, etc. hence, alternate drugs like paracetamol (PCM) and diclofenac are commonly used. In this study, we have compared the analgesic efficacy and any associated side effects of the two commonly used non-opioid NSAIDS namely paracetamol and diclofenac.

Methods: We compared 50 patients undergoing laparoscopic cholecystectomy in ASA I and II. They were randomly divided into two groups, Group A and Group B. Group A was administered intravenous PCM and Group B was administered injection diclofenac sodium. Postoperatively, these patients were assessed for pain, blood pressure, respiratory rate, and presence of any side effects like nausea, vomiting or any respiratory discomfort.

Results: The mean DBP, MAP and VAS score was significantly (p-value <0.05) in Group A as compared to Group B patients at 4, 8, 12 and 24 hours postoperatively. There was no statistically significant difference in mean SBP and O₂ saturation in both groups. The mean pulse rate was lower in Group A as compared to Group B at 8, 12 and 24 hours.

Conclusions: This study concluded that postoperative PCM infusion provided better analgesia for a prolonged period of time with minimal side effects.

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Author Biography

Anurag Bijalwan, Department of General Surgery, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand

Assistant Professor ,Department of Surgery,

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