Isolated vulvo-vaginal Crohn’s disease: case report of the rare entity

Authors

  • Ashwath Narayan Ramji Department of Surgery, Kempegowda Institute of Medical Sciences, Bangalore, Karnataka

DOI:

https://doi.org/10.18203/2349-2902.isj20191287

Keywords:

Crohn’s disease, Vulva, Inflammatory bowel disease

Abstract

The vulva is a rare site for extra-intestinal manifestation of Crohn’s disease, and is usually a late feature of severe, fulminant, unrelenting disease. These islands of granulomatous tissue in the female genitalia are considered “metastatic” deposits as they are separated from the intestinal lesions by healthy tissue. Very rarely, Crohn’s disease may manifest first in an extra-intestinal site, without any bowel lesions. In extremely rare cases, the genitalia is the site of isolated primary Crohn’s disease and serves as a harbinger for bowel lesions.

References

Laftah Z, Bailey C, Zaheri S, Setterfield J, Fuller LC, Lewis F. Vulval Crohn's disease: a clinical study of 22 patients. J Crohns Colitis. 2015;9:318–25.

Barret M, de Parades V, Battistella M, Sokol H, Lemarchand N, Marteau P. Crohn's disease of the vulva. J Crohns Colitis. 2014;8:563–70.

Das D, Gupta B, Saha M. Metastatic vulvar Crohn's disease-A rare case report and short review of literature. Indian J Dermatol. 2016;61:70-4.

Parks AG, Morson BC, Pegum JS. Crohn’s disease with cutaneous involvement. Proc R Soc Med. 1965;58:241–2.

Reitsma W, Wiegman MJ, Damstra RJ. Penile and scrotal lymphedema as an unusual presentation of Crohn's disease: case report and review of the literature. Lymphology. 2012;45(1):37.

Hamilton PA, Brown P, Davies JD, Salmon PR, Crow KD. Crohn's disease: an unusual cause of dyspareunia. Br Med J. 1977;2(6079):101.

Al-Niaimi F, Lyon C. Vulval Crohn’s Disease in Childhood. Dermatol Ther (Heidelb). 2013;3(2):199-202.

Farhi D, Wendling J, Molinari E, Raynal J, Carcelain G, Morand P, et al. Non-sexually related acute genital ulcers in 13 pubertal girls: a clinical and microbiological study. Arch Dermatol. 2009;145:38-45.

Madnani NA, Desai D, Gandhi N, Khan KJ. Isolated Crohn's disease of the vulva. Indian J Dermatol Venereol Leprol. 2011;77:342–4.

Brandt LJ, Bernstein LH, Boley SJ, Frank MS. Metronidazole therapy for perineal Crohn's disease: A follow-up study. Gastroenterology. 1982;83:383-7.

Preston PW, Hudson N, Lewis FM. Treatment of vulval Crohn's disease with infliximab. Clin Experimental Dermatol. 2006;31(3):378.

Feller ER, Ribaudo S, Jackson ND. Gynecologic aspects of Crohn’s disease. Am Fam Physician. 2001;64:1725–8.

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Published

2019-03-26

Issue

Section

Case Reports