Published: 2019-03-26

Oncocytoma: a mystifying parotid mass

Jeevan G. Sanjive, N. S. Reddy, V. Soundara Rajan


Parotid oncocytoma presents in less than 1% of salivary gland tumors. Therefore, there are only very few reported cases in literature. This tumor is often diagnosed in elderly age group. It is often misdiagnosed clinically as pleomorphic adenoma, hemangioma or Warthin’s tumor. CT imaging usually shows an enhancing lobulated mass; however, it cannot exactly diagnose oncocytoma. It can be confirmed only by histopathological examination. This case report is of an Indian female of 66 years with parotid swelling who underwent total conservative parotidectomy. Post operatively, patient has no residual disease and complications.


Parotid, Oncocytoma, Rare salivary gland tumor

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Sepúlveda I, Platín E, Spencer ML, Mucientes P, Frelinghuysen M, Ortega P, et al. Oncocytoma of the Parotid Gland: A Case Report and Review of the Literature. Case Rep Oncol. 2014;7:109–16.

Brandwein MS, Huvos AG. Oncocytic tumors of major salivary glands. A study of 68 cases with follow-up of 44 patients. Am J Surg Pathol. 1991;15:514-28.

Seifert G. Tumour-like lesions of the salivary glands. The new WHO classification. Pathol Res Pract 1992;188:836-46.

Huvos AG. Oncocytoma. In:Barnes L, Eveson JW, Reichert P, Sidransky D (eds). World Health Organization classification of tumors:pathology and genetics, head and neck tumors. Lyon: IARC Press. 2005: 242-243.

Kontaxis A, Zanarotti U, Kainz J, Beham A. Diffuse hyperplastic oncocytosis of the parotid gland. Laryngorhinootologic. 2004;83:185-8

Prabhakaran SS, Chen F, Aguirre A. Oncocytoma of the parotid gland and its mimickers: a comprehensive review. NAJMS 2010;3:171-80.

Capone RB, Ha PK, Westra WH, Pilkington TM, Sciubba JJ, Koch WM, et al. Oncocytic neoplasms of the parotid gland: a 16 year institutional review. Otolaryngol Head Neck Surg. 2002;126:657–62.

Lewis PD, Baxter P, Paul Griffiths A, Parry JM, Skibinski DO. Detection of damage to the mitochondrial genome in the oncocytic cells of Warthin’s tumour. J Pathol. 2000;191:274-81.

Tandler B. Fine structure of oncocytes in human salivary glands. Virchows Arch Pathol Anat Physiol Klin Med. 1966;341:317-26.

Araki Y, Sakaguchi R:Synchronous oncocytoma and Warthin’s tumor in the ipsilateral parotid gland. Auris Nasus Larynx. 2004;31:73–8.