Proportions and reasons for breast conservation surgery and modified radical mastectomy in early breast carcinoma
DOI:
https://doi.org/10.18203/2349-2902.isj20192964Keywords:
Breast conservation surgery, Early breast cancer, Modified radical mastectomyAbstract
Background: Breast cancer is a common cancer among women in India and its incidence is increasing in an alarming rate. There is a paradigm shift in the management of early breast cancer with more emphasis given to breast conservation treatments. This study aimed to assess the proportion of patient underwent breast conservation surgery and reasons to choose breast conservation surgery or modified radical mastectomy in early breast cancer.
Methods: Information of 41 patients with early breast carcinoma who attended the institute during the study period and who can choose either modified radical mastectomy or breast conservation surgery depending on their wish are included in the study group and the data thus obtained was entered in MS Excel data sheet and analysed using SPSS 16 software.
Results: It was observed that the proportion of women selecting breast conserving therapy increased with improved literacy status. Similarly, menstrual status and location of tumor do have an influence in choosing breast conserving surgery with significant statistical correlation. However, unlike the previous studies we did not find any statistically significant association between age and surgical decision. Similarly, place of residence, and employment status of the patient does not influence the decision to undergo breast conservation surgery.
Conclusions: We have to create awareness in the society about the safety of breast conservation treatment to popularize this modality of treatment there by more and more organs can be preserved.
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References
Nandakumar A. National Cancer Registry Programme, Indian Council of Medical Research, Consolidated report of the population based cancer registries, New Delhi, India; 1990-96.
National Cancer Registry Programme. Ten year consolidated report of the hospital based cancer registries 1984-1993. An assessment of the burden and care of cancer patients. New Delhi: Indian Council Med Res; 2001.
National Cancer Registry Programme. Consolidated report of the population based cancer registries 1990-1996. New Delhi: Indian Council Med Res; 2001.
Sen U, Sankaranarayanan R, Mandal S, Ramanakumar AV, Parkin DM, Siddiqi M. Cancer patterns in eastern India: the first report of the Kolkata cancer registry. Int J Cancer. 2002;100:86-91.
Halsted WS. The results of radical operations for the cure of carcinoma of the breast. Ann Surg. 1907;46(1).
Livingston SF, Arlen M. The extended extrapleural radical mastectomy: its role in the treatment of carcinoma of the breast Ann Surg. 1974;179(3):260-5.
Arhelger SW, Lewis FJ, Wangensteen OH. The extended or super-radical mastectomy for carcinoma of the breast. Surg Clin North Am. 1956:1051-63.
Veronesi U, Valagussa P. Inefficacy of internal mammary nodes dissection in breast cancer surgery. Cancer. 1981;47(1):170.
Houssami N, Macaskill P, Marinovich ML, Morrow M. The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: a meta-analysis. Ann Surg Oncol. 2014;21(3):717-30.
Moran MS, Schnitt SJ, Giuliano AE, Harris JR, Khan SA, Horton J, et al. Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. Ann Surg Oncol. 2014;21(3):704.
Buchholz TA, Somerfield MR, Griggs JJ, El-Eid S, Hammond ME, Lyman GH, et al. Margins for breast-conserving surgery with whole-breast irradiation in stage I and II invasive breast cancer: American Society of Clinical Oncology endorsement of the Society of Surgical Oncology/American Society for Radiation Oncology consensus guideline. J Clin Oncol. 2014;32(14):1502-6.
Bodilsen A, Bjerre K, Offersen BV, Vahl P, Amby N, Dixon JM, et al. Importance of margin width in breast-conserving treatment of early breast cancer. J Surg Oncol. 2016;113(6):609-15.
Morrow M, Strom EA, Bassett LW, Dershaw DD, Fowble B, Giuliano A, et al. Standard for breast conservation therapy in the management of invasive breast carcinoma. CA Cancer J Clin. 2002;52(5):277.
Blichert-Toft M, Rose C, Andersen JA, Overgaard M, Axelsson CK, Andersen KW, et al. Randomized trial comparing breast conservation therapy with mastectomy: six years of life-table analysis. Danish Breast Cancer Cooperative Group. J Natl Cancer Inst Monogr. 1992;(11):19-25.
Van Dongen JA, Voogd AC, Fentiman IS, Legrand C, Sylvester RJ, Tong D, et al. Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 Trial. J Natl Cancer Inst. 2000;92(14):1143.
Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347(16):1233.
Veronesi U, Cascinelli N, Mariani L, Greco M, Saccozzi R, Luini A, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347(16):1227.
Scarth H, Cantin J, Levine M, Clinical practice guidelines for the care and treatment of breast cancer: mastectomy or lumpectomy? The choice of operation for clinical stages I and II breast cancer (summary of the 2002 update). Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer. CMAJ. 2002;167(2):154.
Clarke M, Collins R, Darby S, Davies C, Elphinstone P, Evans E, et al. Early Breast Cancer Trialists' Collaborative Group (EBCTCG) .Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trial. Lancet. 2005;366(9503):2087.
Katz SJ, Lantz PM, Janz NK, Fagerlin A, Schwartz K, Liu L, et al. Patient involvement in surgery treatment decisions for breast cancer. J Clin Oncol. 2005;23(24):5526.
Nattinger AB, Gottlieb MS, Veum J, Yahnke D, Goodwin JS. Geographic variation in the use of breast-conserving treatment for breast cancer. N Engl J Med. 1992;326(17):1102.
Habermann EB, Abbott A, Parsons HM, Virnig BA, Al-Refaie WB, Tuttle TM. Are mastectomy rates really increasing in the United States. J Clin Oncol. 2010 Jul 20;28(21):3437-41.
Garcia-Etienne CA, Tomatis M, Heil J, Friedrichs K, Kreienberg R, Denk A, et al. Mastectomy trends for early-stage breast cancer: a report from the EUSOMA multi-institutional European database. European J Cancer. 2012;48(13):1947-56.
Agarval G, Ramakant P, Forgach ER, Rendon JC, Chaparro JM, et al. Breast cancer care in developed countries. World J Surg. 2009;33:2069-76.
Dinshaw KA, Badrukkar AN, Chinoy RF, Sarin R, Badwe R, Hawaldar R. Profile of prognostic factors in 1022 Indian women with early stage breast cancer treated with breast conserving therapy. Int J Radiat Oncol Biol Phys. 2005;63:1132-41.
Narendra H, Roy S. Breast conserving surgery for breast cancer: Single institutional experience from Southern India. Indian J Cancer. 2011;48:415-22.
Kuraparthy S, Reddy KM, Yadagiri LA, Yukla M, Venkata PB, Kadainti SV. Epidemiology and pattern of care for invasive breast carcinoma at a community hospital in South India. Wold J Sug Oncol. 2007;5:56.
Agarval S, Goel AK, Lal P. Participation in decision making regarding type of surgery and treatment-related statics in North Indian women with early breast cancer. J Can. Res Ther. 2012;8:222-5.
Matsuno RK, Anderson WF, Yamamoto S, Tsukuma H, Pfeiffer RM, Kobayashi K, et al. Early-and late-onset breast cancer types among women in the United States and Japan. Cancer Epidemiol Prevention Biomarkers. 2007;16(7):1437-42.
Walsh Dicks EL. Surgery for breast cancer in ST. John’s: the statistics, the surgeons’ view; 1999.