Largest mucoepidermoid carcinoma of parotid gland in the world


  • Abhishek Kumar Department of General Surgery, KIMS, Hubli, Karnataka
  • Vasant Teggimani Department of General Surgery, KIMS, Hubli, Karnataka
  • Ramesh Hosamani Department of General Surgery, KIMS, Hubli, Karnataka
  • Prathamesh Chandrapattan Department of General Surgery, KIMS, Hubli, Karnataka
  • Aboli Koranne Department of General Surgery, KIMS, Hubli, Karnataka



Fine needle aspiration cytology, Mucoepidermoid carcinoma


Mucoepidermoid carcinoma (MEC) is the most common malignant neoplasm of the major salivary glands, accounting for 15.5% of all cases benign and malignant.1 It has multiple types of morphological variants and thus poses a significant challenge in diagnosis on Fine needle aspiration cytology (FNAC). The aim of this article is to report a case of MEC in a 70-years-old male patient who presented with a painless firm fluctuant swelling in left preauricular area on left cheek to Karnataka Institute of Medical Sciences, Hubli. Detailed history was noted, and the swelling was examined clinically. Radiological investigations were carried out. Fine-needle aspiration cytology was done for the lesion and report suggested tumor of the parotid gland. Total parotidectomy procedure was done. There were no intra operative complications and post operatively there was grade 4 Housemann Brackmann facial nerve palsy on left side. The weight of the tumor was 1.45 kg. The histologic picture confirmed that the tumor was MEC of parotid gland. Through this article we want to report the management of giant MEC, the largest to be reported in world literature. 

Author Biography

Abhishek Kumar, Department of General Surgery, KIMS, Hubli, Karnataka



Stewart FW, Foote FW, Becker WF. Muco-epidermoidtumors of salivary glands. Ann Surg. 1945;122(5):820-44.

Ozawa H, Tomita T, Sakamoto K, Tagawa T, Fuji R, Kanzaki S, et al. Epidermoid Carcinoma of the Head and Neck Clinical Analysis of 43 Patients. Japan J Clin Oncol. 2008;38(6):414-8.

Chenevert J, Barnes LE, Chiosea SI. Mucoepidermoid Carcinoma: A Five Decade Journey. Virchows Arch. 2011;458(2):133-40.

Weerakkody Y, Gaillard F. Mucoepidermoid Carcinoma of the Salivary Glands. Available at: Accessed on 5 October 2013.

Fortson JK, Su R, Patel VG, Lawrence GE, Sarcoidosis presenting as chronic sinusitis with orbital and intracranial extension. Am Surg. 2015;81(6):E266-8.

Goode RK, Auclair PL, Ellis GL. Mucoepidermoid carcinoma of the major salivary glands. Cancer. 1998;82(7):1217-24.

Brandwein MS, Ivanov K, Wallace DI, Hille JJ, Wang B, Fahmy A, et al. Mucoepidermoid carcinoma: a clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol. 2001;25(7):835-45.

DeVita, Hellman and Rosenberg's Cancer: Principles and Practice of Oncology (Cancer: Principles & Practice (DeVita). LWW; Ninth, North American edition, 2011.

Califano L, Zupi A, Massari PS, Giardino C. Indication for neck dissection in carcinoma of the parotid gland: our experience on 39 cases. Int Surg. 1993;78(4):347-9.






Case Reports