A clinical study of incidence of malignancy in solitary thyroid nodule in a tertiary care hospital

Authors

  • Palani V. Department of General Surgery, ACS Medical College, Chennai, Tamil Nadu, India
  • Reshma S. Department of General Surgery, ACS Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-2902.isj20185490

Keywords:

Age, Incidence, Malignancy, Sex, Solitary thyroid nodule

Abstract

Background: Thyroid nodules are common endocrine problem. A discrete swelling in an otherwise impalpable gland is termed as solitary nodule of thyroid. Solitary nodules have a high likelihood of being malignant. They should be characterized properly for optimum management. Aim of the study is to identify the incidence of malignancy in solitary nodule thyroid.

Methods: A prospective study had been carried out from January 2018 to October 2018, in the Department of General surgery, ACS Medical College and Hospital, Chennai, India. Fifty patients, who presented with solitary thyroid swelling were examined clinically and confirmed after taking a detailed history and underwent thyroid surgery were included in this study. The histopathological reports were evaluated by standard statistical methods.

Results: There were 50 cases of clinically detected solitary thyroid nodule with female preponderance more than males. The mean age of the incidence of solitary thyroid nodule is 35years. The incidence of malignancy in solitary thyroid nodule is 20%.

Conclusions: It is concluded from the present study that 20% of solitary thyroid nodules are malignant, with female preponderance and a mean age of solitary thyroid nodule is 35years.

References

Tai JD, Yang JL, Wu SC, Wang BW, Chang CJ. Risk factors for malignancy in patients with solitary thyroid nodules and their impact on the management. J Cancer Res Therpeut. 2012;8(3):379-83.

Hegedüs L. The thyroid nodule. New Eng J Med. 2004 Oct 21;351(17):1764-71.

Yeung MJ, Serpell JW. Management of the solitary thyroid nodule. Oncologist. 2008 Feb 1;13(2):105-12.

Usha VM, Sundaram KR, Unnikrishnan AG, Jayakumar RV, Nair V, Kumar H. High prevalence of undetected thyroid disorders in an iodine sufficient adult south Indian population. Journal of the Indian Med Assoc. 2009 Feb;107(2):72-7.

Unnikrishnan AG, Kalra S, Baruah M, Nair G, Nair V, Bantwal G, et al. Endocrine Society of India management guidelines for patients with thyroid nodules: a position statement. Indian J Endocrinol Metabolism. 2011 Jan;15(1):2.

Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA. 2006 May 10;295(18):2164-7.

Gupta M, Gupta S, Gupta VB. Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. J Thyroid Res. 2010;2010:379051.

Iqbal M, Mehmood Z, Rasul S, Inamullah H, Shah SS, Bokhari I. Carcinoma thyroid in multi and in inodular goiter. J Coll Physicians Surg Pak. 2010;20:310-2.

Aggarwal SK, Jayaram GI, Kakar AR, Goel GD, Prakash RA, Pant CS. Fine needle aspiration cytologic diagnosis of the solitary cold thyroid nodule. Comparison with ultrasonography, radionuclide perfusion study and xeroradiography. Acta Cytologica. 1989;33(1):41-7.

Anitha S, Ravimohan TR. A study of incidence of malignancy in solitary nodule of thyroid. J Contemp Med Res. 2016;3(4):993-5.

Lundgren CI, Stalberg P, Grodski S, Sidhu S, Sywak M, Delbridge L. Minimally invasive thyroid surgery for diagnostic excision of solitary thyroid nodules. Asian J Surg. 2007 Oct 1;30(4):250-4.

Hossain MA, Sarkar MZ, Dutta UK, Karim MA, Alam MZ. Frequency of Malignancy in solitary Thyroid nodule and Multi-nodular Goitre. Bangladesh J Otorhinolaryngol. 2015 Feb 9;20(2):55-9.

Akhtar N, Buzdar MU, Khan MA. Frequency of Malignancy in solitary thyroid nodule. PJMHS. 2015;9(3):983-5.

Babu R, Shyamala M, Reddy SK. Malignant incidence in solitary nodule thyroid - a clinical study. IJAR. 2015;5(2).

Downloads

Published

2018-12-27

Issue

Section

Original Research Articles