Clinico-pathological correlation of abdominal lymphadenopathy

Yashpal Ramole, Vijay Tekam


Background: This study “clinico-pathological correlation of abdominal lymphadenopathy" intended to know the various etiological causes behind the abdominal lymphadenopathy and different modes of presentation which can help in treatment and prognosis in our setup which helps in better management of these cases thus helping to improve prognosis.

Methods: The" Clinico-Pathological Correlation of Abdominal Lymphadenopathy is a clinical study of 250 consecutive cases of abdominal Lymphadenopathy which were found during intraoperative laparotomy in Hamidia Hospital (Gandhi Medical College), Bhopal. This is observational study will be carried out in the Department of Surgery, Gandhi Medical College. Total 250 consecutive cases will be included in this study having per-operative findings of lymphadenopathy, where laparotomy will be done for various regions. Prior to surgery thorough history will be taken and meticulous physical examination will be performed. Necessary laboratory and imaging studies shall do to establish the diagnosis.

Results: Tuberculosis is one of the common causes of Abdomen lymphadenopathy. Age incidence more in males and in second and third decade of life is more common. Abdominal pain, loss of weight and appetite with bowel disturbances are the common clinical manifestation. It is obvious from this study that tuberculosis is a problem in our country. Regarding the abdominal tuberculosis, the diagnostic problem persists for those patients where pulmonary tuberculosis is not obvious. Most tubercular patients present with perforation peritonitis.

Conclusions: This study support fact that abdominal lymphadenopathy is important indicator of underlying cause of pathogenesis from which we reach the diagnosis. In present study in 10% cases only lymph nodes are positive for tuberculosis without tissue diagnosis, which can be treated to prevent the further complications.


Abdomen, Carcinoma, Lymphadenopathy, Laprotomy, Tuberculosis

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Mostanzid SM, Ashraf F, Haque M. Clinico-pathological correlation of abdominal lymphadenopathy. TAJ. J Teachers Assoc. 2008;21(2):126-31.

Khan MR, Khan IR, Pal KM. Diagnostic issues in abdominal tuberculosis. J Pak Med Assoc. 2001;51(4):138-42.

Inderbir Singh: Textbook of Human Histology with colour atlas practical. JPB; Sixth edition; 2011.

Ghirardelli ML, Jemos V, Gobbi PG. Diagnostic approach to lymph node enlargement. Haematologica. 1999;84(3):242-7.

Gupta SC, Gupta AK, Keswani NK, Singh PA, Tripathi AK, Krishna V. Pathology of tropical appendicitis. J Clin Patrioi. 1989:42:1169-72.

Al-Quorain AA, Satti MB, Al-Freihi HM, Al-Gindan YM, Al-Awad N. Abdominal tuberculosis in Saudi Arabia: a clinicopathological study of 65 cases. Am J Gastroenterol. 1993;88(1).

Sikorska-Wiśniewska G, Liberek A, Góra-Gebka M, Bako W, Marek A, Szlagatys-Sidorkiewicz A, Jankowska A. Mesenteric lymphadenopathy-a valid health problem in children. Medycyna wieku rozwojowego. 2006;10(2):453-62.

Gray H, Goss CM. Anatomy of the human body. Am J Physical Med and Rehabilitation. 1974;53(6):293.

Veeragandham RS, Lynch FP, Canty TG, Collins DL, Dankner WM. Abdominal tuberculosis in children: review of 26 cases. J Pediatr Surg. 1996;31(1):170-6.

Rangabashyam N. Abdominal tuberculosis. In: Morris PJ. Malt RA. Editors Oxford textbook of surgery. New York: Oxford University Press; 1994:2484-92.

Mann CV, Russel RCG. Williams NS, editors. Bailey and Love's short practice of surgery- London: English Language Book Society; 1995.

Marshall JB. Tuberculosis of the gastrointestinal tract and peritoneum. Am J Gastroenterol. 1993:88:989-99.

Pimparkar BD, DondeUM. Intestinal tuberculosis I. Clinical and radiological studies. J Assoc Physicians India. 1974:22:205-18.

Singh V, Jain AK, Agrawal AK, Gupta S, Khanna S, Khanna AK. Clinicopathological profile of abdominal tuberculosis. Br J Clin Prac. 1995;49(1):22-4.

Linehan WM. DeVita, Hellmand, and Rosenberg's cancer: principles and practice of oncology. Cancer of the Kidney. 2011:1161-82.

Varshney S, Johnson CD. Tuberculosis of the pancreas. Postgrad Med J. 1995:71:564-6.

Mann CV, Russel RCG. Williams NS, editors. Bailey and Love's short practice of surgery- London: English Language Book Society; 1995.

Sohocky S, Tuberculous peritonitis: a review of 100 cases. Am Rev Respir Dis. 1967:95:398-401.

Singh MM, Bhan-ava AN, Jain KP. Tuberculosis peritonitis: an evaluation of pathogenic mechanisms, diagnostic procedures and therapeutic measures. N Eng IJ Med. 1969:289:1091-4.

Dineeen P, Homan WP, Grafe WR. Tuberculous peritonitis: 43 years' expereince in diagnosis and treatment. Ann Surg. 1976;184(6):717.

Manohar A, Sirnjee AE, Haffejee AA, Pettengell KE. Symptoms and investigative findings in 145 patients with tuberculous peritonitis diagnosed by peritoneoscopy and biopsy over a five-year period. Gut. 1990;31:1130-2.

Bhargava DK, Chopra P, Nijhawan S, Dasarathy S, Kushwaha AK. Peritoneal tuberculosis: laparoscopic patterns and its diagnostic accuracy. Am J Gastroenterol. 1992;87(1).

Hyman S, Villa F, Alvarez S, Steigmann F. The enigma of tuberculous peritonitis. Gastroenterol. 1962;42(1):1-6.

Aguado JM, Pons F, Casafont F, San GM, Valle R. Tuberculous peritonitis: a study comparing cirrhotic and noncirrhotic patients. J Clinical Gastroenterol. 1990;12(5):550-4.

Cheng IK, Chan PC, Chan MK. Tuberculous peritonitis complicating long-term peritoneal dialysis. Am J Nephrol. 1989;9(2):155-61.

Tribedi BD, Gupta DM. Intestinal tuberculosis in Bengal. J Indian Med Assoc. 1941;11:41.

Ukil AC. Early diagnosis and treatment of intestinal tuberculosis. Indian Med Gazette. 1942:77:613.

Chuttani HK. Intestinal tuberculosis. In: Modern trends ingastroenterology. Card Wl, Creamer B. editors. London: Butter-worth: 1970:309-27.

Bhansali SK, Seilina JR. Intestinal obstruction: a clinical analysis of 348 rases. Indian J Surg. 1970:32:57-70.

Bhansali SK. Gastrointestinal perforations: clinical study of 96 cases. J Postgrad Med. 1967:13:1-12.

Pimparkar BD, Dondel lM. Intestinal tuberculosis I. Clinical and radiological studies. J Assoc Physicians India. 1974:22:205-18.

Das P, Shukla HS. Clinical diagnosis of abdominal tuberculosis. Br J Surg. 1976:63:941-6.