Antimicrobial sensitivity in urinary tract obstruction due to calculus: a study of 50 cases
DOI:
https://doi.org/10.18203/2349-2902.isj20184259Keywords:
Adenocarcinoma, Colorectal, Carcinoma, Colonoscopy, RetrospectiveAbstract
Background: The urinary tract obstruction occurs due to several causes. one of the most important cause of obstruction is urinary calculus. urinary calculi are the third most common affliction of the urinary tract exceeded only by urinary tract infection and pathology of prostate. Improvement of the medical facility and increased health consciousness has resulted in more patients presenting with early urinary tract obstruction due stone.
Methods: This is prospective study. It was conducted from July 2017 to August 2018 at GMERS medical college Valsad. A Study of 50 cases was carried out, after thorough clinical examination and necessary investigations, patients were subjected to x ray KUB, ultrasonography, intravenous pyelography. The samples were cultured & Antimicrobial sensitivity determined.
Results: Escherichia coli is the commonest urinary pathogen causing 60 -90 % of infection, but in this study 72% of patient came infected with Escherichia coli 16% came infected with Klebsiella. Infection of anterior urinary tract (Urethritis) is mainly caused by N. Gonrrhoeae, staphylococci and chlamydia. Gentamicin is found to be most effective drug (78% sensitivity) in present series this is followed by Gatifloxacin (60% sensitivity), Septran (36% sensitivity) & Cefotaxime (34% sensitivity).
Conclusions: It is concluded that most of the urinary tract infections in human are caused by Escherichia coli with more sensitivity to Gentamicin.
References
Biadglegn F, Abera B. Antimicrobial resistance patterns of bacterial isolates from urinary tract infections at Felege Hiwot Referral Hospital, Ethiopia. Ethiop J Health Dev. 2009;23:236-8.
Akoachere JF, Yvonne S, Akum NH, Seraphine EN. Etiologic profile and antimicrobial susceptibility of community-acquired urinary tract infection in two Cameroonian towns. BMC Res Notes. 2012;5:219.
Stamm WE. Scientific and clinical challenges in the management of urinary tract infections. The Am J Med. 2002;113(1):1-4.
Sepsis and kidney stones, Sepsis Alliance. Available at https://www.sepsis.org/sepsis-and/kidney-stones/.
Blondeau JM. Current issues in the management of urinary tract infections. Drugs. 2004;64(6):611-28.
Ashkenazi S, Even-Tov SM, Samra Z, Dinari G. Uropathogens of various childhood populations and their antibiotic susceptibility. Pediatr Inf Dis J. 1991;10(10):742-6.
Akram M, Shahid M, Khan AU. Etiology and antibiotic resistance patterns of community-acquired urinary tract infections in JNMC Hospital Aligarh, India. Ann Clin Microbiol Antimicrob. 2007;6:4.
Ullah F, Malik S, Ahmed J. Antibiotic susceptibility pattern and ESBL prevalence in nosocomial Escherichia coli from urinary tract infections in Pakistan. Afr J Biotechnol. 2009;8:3921-6.
Khan AU, Zaman MS. Multiple drug resistance pattern in urinary tract infection patients in Aligarh. Biomed Res. 2006;17:179-81.
Medina-Bambardo D, Segui-Diaz M, Roca-Fusalba C, Llobera J. The Dysuria Team. What is the predictive value of urinary symptoms for diagnosing urinary tract infection in women? Fam Pract. 2003;20:103-7.
Shaifali I, Gupta U, Mahmood SE, Ahmed J. Antibiotic susceptibility patterns of urinary pathogens in female outpatients. North Am J Med Sci. 2012;4(4):163.
Kothari A, Sagar V. Antibiotic resistance in pathogens causing community-acquired urinary tract infections in India: a multicenter study. J Infect Dev Ctries. 2008;2:354-8.
Savas L, Guvel S, Onlen Y, Savas N, Duran N. Nosocomial urinary tract infections: Micro-organisms, antibiotic sensitivities and risk factors. West Indian Med J. 2006;55:188.
Colgan R, Willams M. Diagnosis and treatment of acute uncomplicated cystitis Am Fam Physician. 2011;84:771-6.