Carcinoma stomach and its analysis on presentation in Government Vellore Medical College: institutional study

Authors

  • Rathi Thilagam N. Department of Radiotherapy, Government Vellore Medical College Hospital, Vellore, Tamil Nadu, India
  • Anbalagan P. Department of General Surgery, Government Thiruvannamalai Medical College Hospital, Thiruvannamalai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-2902.isj20184070

Keywords:

Carcinoma Stomach, Risk factors, Staging

Abstract

Background: Cancer stomach is one of the five commonest cancer contributing to cancer mortality and morbidity.It is a curable disease if detected early but unfortunately most of the patients present in the locally advanced stage. Stage at presentation is the single most important prognostic factorand which determines the resectability of the disease.

Methods: The present study is a Retrospective study and the study period was between January 2016 to January 2018. The inclusion Criteria were all patients above 30 years of age reporting with histopathological diagnosis of carcinoma Stomach to determine the age at presentation, stage at presentation, gender distribution, type of surgery done and the common histopathological diagnosis.

Results: This study showed highest incidence of carcinoma stomach in the age group of 30- 50yrs.Male and female ratio was1.4:1. Around 58% patient presented in the locally advanced stage stage III A, IIIB and IIIC and 8% with liver metastasis.As already mentioned most of the patient present to the hospital in a late stage and stage is the most important prognostic factor.

Conclusions: To conclude the present study showed a high incidence in the age group 30 to 50yrs and the most common affected gender was male. Pylorus and Pyloric antrum was the common site of presentation. Most of the patient around 58% presented in a locally advanced stage.

References

Phuhan RK, Zomavia E, Hazarika NC, Baruah D, Mahanta J. High prevalence of stomach cancer among the people of Mizoram in India Currsci. 2004;87:285-6.

Phuhan RK, Zomavia E, Narain K, Hazarika NC, Mahanta J. Tobacco use and stomach cancer in Mizoram India. Cancer epidemiological Biomarkers. Prev. 2005;14;1892-6.

Alberts SR, Cervantes A, Van de Velde CJ. Gastric cancer: epidemiology, pathology and treatment. Ann oncol. 2003;14ii 31-6.

Pavithran K, Doval DC, Pandey KK. Gastric cancer in India. Gastric Cancer. 2002;5(4):0240-3.

Sumathi B, Ramalingam S, Navaneetham V, Jayanthi V. Risk factors for gastric cancer in south India. Singapore Med J. 2009;50:147-51.

Shrikhande SV, Shukla PJ, Qureshi S, Siddachari R, Upasani V, Ramadwar M, et al. D2 lymphadenectomy for gastric cancer in Tata Memorial Hospital: Indian data can now be incorporated in future international trials. Digestive Surgery. 2006;23(3):192-7.

Zali K, Rezaei-Tavirani M, Azodi M. Gasrtic cancer: prevention, risk factors and treatment. Gastroenterol Hepatol Bed Bench. 2011;4(4):175-85.

Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893-917.

Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol. 2006;24:2137-50.

Kim JP, Lee JH, Kim SJ, Yu HJ, Yang HK. Clinicopathologic characteristics and prognostic factors in 10 783 patients with gastric cancer. Gastric Cancer. 1998;1:125-33.

Hundahl SA, Phillips JL, Menck HR. The National cancer data base report on poor survival of U.S. gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer staging, proximal disease, and the “different disease” hypothesis. Cancer. 2000;88:921-32.

Msika S, Benhamiche AM, Jouve JL, Rat P, Faivre J. Prognostic factors after curative resection for gastric cancer. A population-based study. Eur J Cancer. 2000;36:390-6.

Dikshit RP, Mathur G, Mhatre S, Yeole BB. Epidemiological review of gastric cancer in India. Indian journal of medical and paediatric oncology: official J Indian Society of Med Paediatr Oncol. 2011;32(1):3.

Mihamani M, IIhan E, Idiz UO, Alemdar A, Demir U. World J Gastroenterol. 2016;22(17): 4307-20.

Kao YC, Fang WL, Wang RF, Li AF, Yang MH, Wu CW. Clinicopathological differences in signet ring cell adenocarcinoma between early and advanced gastric cancer. Gastric Cancer. 2018:1-9.

Downloads

Published

2018-09-25

Issue

Section

Original Research Articles