Analytical study of bladder tumor
DOI:
https://doi.org/10.18203/2349-2902.isj20182938Keywords:
Bladder tumor, Cystectomy, Transurethral resection of bladder tumorAbstract
Background: Treatment of bladder tumor still provides the romance in Urology. The purpose of this study is to study the prevalence of various types of bladder tumors, to compare various treatment modalities for bladder tumors, to study different presentations of patients with bladder tumor.
Methods: The present study was a prospective analytical study of 30 patients of bladder tumor conducted at Dhiraj General Hospital attached to S.B.K.S Medical College from October 2011 to July 2013. All the details of patients in term of demography, risk factors, symptoms and sign, radiological, endoscopic, histopathological features, various treatment modalities offered, and follow-up of patients were studied and analysed using descriptive statistics.
Results: Maximum number of patients was presented in sixth decade of life. Youngest patient was 30 years old and oldest patient was 77 years old. 80% patients were male, and 20% patients were female. History of smoking was present in 22 patients, history of exposure to occupational hazards was present in 4 patients and only 2 patients had positive family history. Majority 93.3% patients were presented with haematuria and 16 patients had anaemia. 15 patients had high grade muscle invasive TCC, followed by 10 patients with low grade non-muscle invasive TCC. 3 patients were having low grade non-muscle invasive SCC, 1 patient was having high grade muscle invasive SCC and 1 patient was having high grade non-muscle invasive TCC.
Conclusions: The findings of the study conclude that TURBT followed by intravesical instillation of BCG gave good results in patients with low grade and high grade non-muscle invasive tumor. For muscle invasive tumor radical cystectomy with urinary diversion is the ideal treatment but TURBT followed by radiotherapy has also given good results with fewer side effects.
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References
Van der Poel HG, Mungan NA, Witjes JA. Bladder cancer in women. Int Urogynecol J Pelvic Floor Dysfunct. 1999;10:207-12.
Lee R, Droller MJ. Natural history of bladder cancer: implications for therapy. Urol Clin North Am. 2000;27:1-14.
Rafique M. Clinico-pathological features of bladder carcinoma in women in Pakistan and smokeless tobacco as a possible risk factor. World J Surg Oncol. 2005;3:53.
Konety BR, Williams RD. Superficial transitional (Ta/T1/CIS) cell carcinoma of the bladder. BJU Int. 2004;94:18-21.
Sherwood BT, Jones GD, Mellon JK, Kockelbergh RC, Steward WP, Symonds RP. Concomitant chemoradiotherapy for muscle-invasive bladder cancer: the way forward for bladder preservation? Clin Oncol (R Coll Radiol). 2005;3:160-6.
Cooke PW, Dunn JA, Latief T, Bathers S, James ND, Wallace DM. Longterm risk of salvage cystectomy after radiotherapy for muscle-invasive bladder cancer. Eur Urol. 2000;38:279-86.
Varkarakis MJ, Gaeta J, Moore RH, Murphy GP. Superficial bladder tumor: Aspects of clinical progression. AJ URO. 1974;4(4):414-2.
Sen U, Sankaranarayanan R, Mandal S, Agnihotram V. Cancer patterns in eastern India: The first report of the Kolkata cancer registry. Int J Cancer. 2002;100(1):86-91.
Joshi HN, Makaju R, Karmacharya A, Karmacharya RM, Shrestha B, Shrestha R, et al. Urinary bladder carcinoma: Impact of smoking, age and its clinico-pathological spectrum. KUMJ. 2013;11:292-5.
Negri E, La Vecchia C. Epidemiology and prevention of bladder cancer. Eur J Cancer Prev. 2001;10:7-14.
Chinnasamy R, Krishnamoorthy S, Joseph L, Kumaresan N, Ramanan V. Clinico-pathological study of bladder cancer in a tertiary care center of South India and Impact of age, gender, and tobacco in causing bladder cancer: a single center experience. Int J Sci Stud. 2016;3(10):72-7.
a Gago-Dominguez M, Esteban Castelao J, Yuan JM, Mimi C. Use of permanent hair dyes and bladder-cancer risk. International J Cancer. 2001;91(4):575-9.
Arlene FK, Patricia H, Robert NH, Ambati SN. Urinary tract infection and risk of bladder cancer. American J Epidemiol. 2003;119(4):510-5.
Srivastava D, Kumar A, Mittal B, Mittal R. Urinary tract infection and risk of bladder cancer. Arch Toxicol. 2004;78(8):430-4.
Piper JM, Tonascia J, Genevieve MM. Heavy analgesic Use and Bladder Cancer. New England J Med. 1985;313(4):292-5.
Arlene FK, Patricia H, Robert NH, Joseph FFJr. Familial and environmental interactions in bladder cancer risk. Int J Cancer. 2006;35(6):703-6.142.
Cristiane MN, Debra TS, Manolis K, Montserrat G. Risk of Bladder Cancer Associated with Family History of Cancer. Cancer Epidemiology, Biomarkers Prevention. 2011;24(2):432-9.
JD Burch, TE Rohan, GR Howe, HA Risch. Haematuria in bladder cancer. Int J Cancer. 1989;44(4):622-8.
Badjatia N, Satyam A, Singh P, Seth A. Presentation of bladder tumor. Urologic Oncolog. 2010;28(4):360-7.
Boman H, Hedelin H, Jacobsson S, Holmäng S. newly diagnosed bladder cancer: the relationship of initial symptoms, degree of microhematuria, tumor marker status, urine cytology. J Urol. 2002;168(5):1955-9.
Donald LL, Brent AB, John DC, James EM. Cancer pattern, spread and management. J Urol. 2007;163(4):11124-9.
Lucia JD, Alan SR, Harold LS, Auguste SF. Rates, Pathology study of cancer of the urinary bladder. J Natl Cancer Inst. 2004;41(3):683-709.
Spencer BA, James EM, Sherlock P. Management of the patient with bladder cancer. Urol North Am. 1994;21(6):763-9.
Hulshof MC, Montserrat G, Baron J, Jung P. Risk and management of bladder cancer. J Natl Cancer Inst. 2004;48(5):573-85.
Alan MN, David SM, Sandy SK, Mark SS. Transurethral bladder tumor resection: intraoperative and postoperative complications. J Urol. 2005;174(6):2307-9.
Angeline SA, Alan RS, John AH, Margaret RK. Bladder tumor management and complications. Int J Cancer. 2004;109(4):581-6.
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