DOI: http://dx.doi.org/10.18203/2349-2902.isj20182395

Pattern of upper gastrointestinal diseases: an audit of 1000 cases based on endoscopic findings from a tertiary care hospital in Mysore

Shashikumar H. B., Madhu B. S., Motati Harshini

Abstract


Background: Fibreoptic endoscopy is a highly efficient diagnostic tool, which is now increasingly being used in the diagnosis of upper gastrointestinal diseases. This study has been carried out to evaluate the distribution of various upper gastrointestinal diseases based on endoscopic findings in a tertiary care hospital in Mysore.

Methods: A cross-sectional study was conducted based on data from endoscopic register of 1000 subjects who underwent endoscopy for various upper gastrointestinal symptoms from 1st January 2017 to 31st December 2017(one year).

Results: Mean age of the study population was 50.23 years (SD-15.46). Minimum age was 12 years and maximum was 88 years. About 44.7% of the study subjects belonged to 40-60 age group.61.6% of the study subjects were males. Most common indication was pain abdomen (32.1%) followed by dysphagia (22.2%). Of the 1000 study subjects 18.6% had normal findings. Most common finding was Gastritis / Duodenitis /Gastric erosions (28%). Malignant lesions were noted among 11.1%, of which esophagus and stomach are 5.4% and 4.9% respectively.

Conclusions: Endoscopic diagnosis is useful for early detection of UGI diseases and helpful for their management.


Keywords


Age, Dysphagia, Mysore, Upper gastrointestinal (UGI) diseases

Full Text:

PDF

References


John FM, Mark R. Gastrointestinal Endoscopy. N Engl J Med. 1991; 325:1142-9.

Khoshbaten M, Naderpour M, Mohammadi G, Alipoor SH, Estakhri R, Fazeli Z. Epidemiology of esophageal lesions in patients with head and neck squamous cell carcinoma. Asian Pacific J Cancer Prev. 2010;11:863-5.

Axon ATR, Bell GD, Jones RH, Quine MA, McCloy RF. Guidelines on appropriate indications for upper gastrointestinal endoscopy. Br Med J. 1995;310(6983):853.

Lieberman DA, De Garmo PL, Fleischer DE, Eisen GM, Helfand M. Patterns of endoscopy use in the United States. Gastroenterol. 2000;118(3):619-24.

Edgarachkar. Structural disorders of the esophagus Clevel and clinic foundation. 2005.

Messner AH, Browne JD, Geisinger KR. Effect of intermittent acid and pepsin exposure on burned esophageal mucosa. 1996. Am J Otolaryngol. 17;(1) 45-9.

Andreollo NA, Lopes LR, Tercioti Jr V, Brandalise NA, Leonardi LS. Barrett's esophagus associated to caustic stenosis of the esophagus. 2003;40(3):148-51.

Tseng YL, Wu MH, Lin MY, Lai WW. Massive upper gastrointestinal bleeding after acid-corrosive injury. World J Surg. 2004;28(1):50-4.

Shaheen N, Provenzale D. The epidemiology of gastroesophageal reflux disease. Am J Med Sci. 2003;326(5):264-73.

Sarıo˘glu M, Kabac¸am G, Bektas M. The change in esophagitis detection rates during the last two decades at an endoscopy cented. Endoscopi. 2009;17:1-5.

Yeh C, Hsu CT, Ho AS, Sampliner RE, Fass R. Erosive Esophagitis and Barrett's Esophagus in Taiwan : a higher frequency than expected. Digestive diseases and sciences. 1997;42(4):702-6.

Pahwa R, Neeta VK, Kohli K. Clinical manifestations, causes and management strategies of peptic ulcer disease. Int J Pharm Sci Drug Res. 2010;2(2):99-106.

Moore M, Gould P, Keary BS. Global urbanization and impact on health. Int J Hyg Environ Health. 2003;206(4-5):269-78.

Awadall HI. Health effect of slums: A consequence of urbanization. Scholarly J Med. 2013;3(1):7-14.

Kurata JH, Nogawa AN. Meta-analysis of risk factors for peptic ulcer. nonsteroidal anti-inflammatory drugs, helicobacter pylori, and smoking. J Clin Gastroenterol. 1997;24(1):2-17.

Aduful HK, Naaeder SB, Darko R, Baako BN, Clegg-Lamptey JN, Nkrumah KN, Adu-Aryee NA, Kyere M. Upper gastrointestinal endoscopy at the korle bu teaching hospital, accra, ghana. Ghana Med J. 2007;41(1):12.

Olokoba AB, Bojuwoye BJ. Indications for oesophagogastroduodenoscopy in Ilorin, Nigeria a 30 month review. Niger J Clin Pract. 2010;13(3): 260-263.

Khan Y, Mohanty SK, Kumar H, Pandey S. Upper gastro instestinal endoscopic findings in patients with dyspepsia: our experience at cims, bilaspur, chhattisgarh, India. IOSR-JDMS, 13, 8-12.

Kochman ML. The Future Use of Endoscopy in Therapeutic Procedures. Gastroenterol Hepatol. 2007;3(11):829.

Thomas V, Jose T, Kumar S. Natural history of bleeding after esophageal variceal eradication in patients with extrahepatic portal venous obstruction; a 20-year follow-up. Indian J Gastroenterol. 2009;28(6):206-11.

Bemeur C, Desjardins P, Butterworth RF. Role of nutrition in the management of hepatic encephalopathy in end-stage liver failure. J Nutr Metab. 2010;489823.

Calderone RA, Fonzi WA. Virulence factors of Candida albicans. Trends Microbiol. 2001;9:327-5.

Vazquez JA, Sobel JD. Mucosal candidiasis. Infect Dis Clin North Am. 2002;16(4):793-820

Islami F, Kamangar F. Helicobacter pylori and esophageal cancer risk- a meta-analysis. Cancer Prev Res.2008;1(5):329-38.

Whiteman DC, Parmar P, Fahey P, Moore SP, Stark M, Zhao ZZ, et al. Association of Helicobacter pylori infection with reduced risk for esophageal cancer is independent of environmental and genetic modifiers. Gastroenterol. 2010;139(1):73-83.

Saha AK, Maitra S, Hazra SC. Epidemiology of gastric cancer in the Gangetic areas of West Bengal. Gastroenterol. 2013;23:2013.

Cam S. Risk of Gastric Cancer in Children with Helicobacter pylori Infection. Asian Pac J Cancer Prev. 2014;15:9905-8.

Vannarath S, Vilaichone RK, Rasachak B, Mairiang P, Yamaoka Y, Shiota S, et al. Virulence genes of Helicobacter pylori in gastritis, peptic ulcer and gastric cancer in Laos. Asian Pac J Cancer Prev. 2014;15(20):9027-31.

Smoot DT, Mobley HLT, Chippenale GR, Lewison JF, Resau JH. Helicobacter pylori urease activity is toxic to human gastric epithelial cells. Infect Immunity. 1990;58(6):1992-4.

Ha NC, Oh ST, Sung JY, Cha KA, Lee MH, Oh BH. Supramolecular assembly and acid resistance of Helicobacter pylori urease. Nat Struct Biol. 2001;8(6):505.

Seifert E, Gail K, Weismüller J. Gastric polypectomy. Endoscopy. 1983;15(01):8-11.

Fatemi SR, Safaee A, Pasha S, Pourhoseingholi MA, Bahrainei R, Molaei M. Evaluation of endoscopic characteristics of upper gastrointestinal polyps in patients with familial adenomatous polyposis. Asian Pac J Cancer Prev. 2014;15(16):6945-8.