The changing trends in epidemiological characteristics of gastric adenocarcinoma: a Tunisian center experience

Rafik Ghrissi; Mohamed amine Elghali; Rim Ghammam; Amine Gouader; Fehmi Hamila; Mohamed Rached Letaief

doi:10.18203/2349-2902.isj20151248

Authors

Rafik Ghrissi Department of General Surgery, Farhat Hached University Hospital, Sousse, Tunisia
Mohamed amine Elghali Department of General Surgery, Farhat Hached University Hospital, Sousse, Tunisia
Rim Ghammam Department Hospital Hygiene and Preventive Medicine, Farhat Hached University Hospital, Sousse, Tunisia
Amine Gouader Department of General Surgery, Farhat Hached University Hospital, Sousse, Tunisia
Fehmi Hamila Department of General Surgery, Farhat Hached University Hospital, Sousse, Tunisia
Mohamed Rached Letaief Department of General Surgery, Farhat Hached University Hospital, Sousse, Tunisia

DOI:

https://doi.org/10.18203/2349-2902.isj20151248

Keywords:

Gastric adenocarcinoma, Cardia tumors, Non-cardia tumors, Signet ring cells adenocarcinoma, Epidemiology

Abstract

Background: Gastric adenocarcinoma is a frequent disease characterized by recent changing trends in epidemiological features, mainly in developed countries. The aim of our study is to describe any changing trends, mainly, in distal and proximal gastric adenocarcinomas rates and signet ring cells adenocarcinomas rate.

Methods: This is a retrospective monocentric study of 169 consecutive cases of primary invasive gastric adenocarcinoma, covering a period of 20 years. We have divided these cases into 2 equal-period groups. The rates of proximal cancers (cardia cancers), distal cancers (non-cardia cancers) and signet ring cells adenocarcinomas had been compared. Other parameters have been studied and compared such as gender, age and surgery types.

Results: There is a statistically significant difference between the 2 groups regarding the rates of signet ring cells adenocarcinoma. The cardia cancer rates and non-cardia cancer rates are not statistically different between the 2 groups (p=0.074). However, there is an increasing trend in cardia cancers rate (7.6% to 16.7%) and a decreasing in non-cardia cancers rate (92.4% to 83.3%). There is no difference in regards to age, sex and type of surgery.

Conclusions: The database of our retrospective study regarding age & sex incidence, clinicopathological features and therapeutic outcome was comparable to other studies in various literatures.

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