Effect of marsupialization on the healing of fistulotomy wounds of simple anal fistula: a randomized control trial
DOI:
https://doi.org/10.18203/2349-2902.isj20181839Keywords:
Anal fistula, Fistulotomy MarsupializationAbstract
Background: An anal fistula is traditionally treated by fistulotomy, adding marsupialization of fistulotomy wounds is optional. The aim of the current study was to compare the outcomes of fistulotomy with marsupialization and fistulotomy alone for simple anal fistula on healing rates and post-operative complications
Methods: 50 patients with simple anal fistula randomly allocated to two groups fistulotomy alone group (F)and fistulotomy with marsupialization group(FM). The primary outcome was the healing time secondary outcomes included postoperative pain, operating time, incontinence and recurrence.
Results: Mean age of group (F) patients was 37.55 ± 1.96 years with a male: female ratio of 19:6 while the mean age of group (FM) patients was 36.30 ± 3.03 years with a male: female ratio of 21:4. Mean operative time in the group (F) was 23.5±3.3 minutes while in the group (FM) It was 29.00± 4.595 minutes difference is statistically significant. Mean time for complete healing in group (F) was 6.9 ±0.73 weeks while in group (FM) was 4.80 ±0.96 weeks difference is significant statistically. Mean postoperative pain score by visual analogue scale in the group (F) was 3.4 ± 1.2 while in the group (FM) it was 3.3 ± 1.3 this difference is statistically non-significant. No recurrences or incontinence.
Conclusions: Study demonstrated faster-wound healing when adding marsupialization to fistulotomy compared to fistulotomy alone. There is an increase operative time with marsupialization. This effect is minimal when compared with the benefits of enhanced healing. Limitations are mainly the inadequate sample size and inadequate follow-up period.
Metrics
References
Rizzo JA, Naig AL, Johnson EK. Anorectal abscess and fistula-in-ano: evidence-based management. Surg Clin North Am. 2010;90:45-68.
Malik AI, Nelson RL, Tou S. Incision and drainage of the perianal abscess with or without treatment of anal fistula. Cochrane Database Syst Rev. 2010;7: CD006827.
Malik AI, Nelson RL. Surgical management of anal fistulae: a systematic review. Colorectal Dis. 2008;10:420-30.
Garcia-Aguilar J, Belmonte C, Wong WD, Goldberg, Madoff RD. Anal fistula surgery. Factors associated with recurrence and incontinence. Dis Colon Rect. 1996;39:723-9.
Jorge J. MN, & Wexner, S. D. (1993). Etiology and management of fecal incontinence. Dis Colon Rect. 1993;36:77-97.
Malouf AJ, Buchanan GN, Carapeti EA, Rao S, Guy RJ, Westcott E, et al. A prospective audit of fistula-in-ano at St. Mark‟s Hospital. Colorectal Dis 2002;4:13-9.
Ho YH, Tan M, Leong AF, Seow-Choen F. Marsupialization of fistulotomy wounds improves healing: a randomized controlled trial. Br J Surg 1998;85:105-7.
Jain BK, Vaibhaw K, Garg PK, Gupta S, Mohanty D. Comparison of a Fistulectomy and a Fistulotomy with Marsupialization in the Management of a Simple Anal Fistula: A Randomized, Controlled Pilot Trial,J Korean Soc Coloproctol. 2012;28:78–82.
Pescatori M, Ayabaca SM, Cafaro D, Iannello A, Magrini S. Marsupialization of fistulotomy and fistulectomy wounds improves healing and decreases bleeding: a randomized controlled trial.Colorectal Dis. 2006;8:11-4.
Kronborg O. To lay open or excise a fistula-in-ano: a randomized trial. Br J Surg. 1985;72:970.
Jacob TJ, Perakath B, Keighley MR. Surgical intervention for anorectal fistula. Cochrane Database Syst Rev. 2010;12:CD006319.
Chucheep Sahakitrungruang C, Pattana-Arun J, Khomvilai S, et al., Marsupialization for simple fistula in ano: a randomized controlled trial. J Med Assoc Thai. 2011;94:699-703.