Chronic cavitatory aspergilloma in an old emaciated patient with review of three cases
Keywords:
Aspergilloma, Cavity, TuberculosisAbstract
Aspergilloma is aspergillus fungus overgrowth, most frequently in upper respiratory passages or lung, in a spatial configuration. Chronic cavitatory or cystic parenchymal disease, causing damage to bronchial tree, predisposes to aspergilloma. It produces significant morbidity and requires early surgical intervention. The controversies still exists regarding medical and surgical management of aspergilloma. With decreasing incidence of tuberculosis, surgery is now less challenging for aspergilloma, with improved outcome, during past three decades. Presenting here is a case of giant aspergilloma involving the left upper and middle lobe, which had been progressively increasing since 15 years, in a patient with no history of tuberculosis, with two more cases, along with symptoms and signs, operative and perioperative management, as well as literature review of this rare, clinically important entity.
References
Vaideeswar P, Prasad S, Deshpande JR, Pandit SP. Invasive pulmonary aspergillosis: a study of 39 cases at autopsy. J Postgrad Med. 2004;50:21-6.
Daly RC, Pairolero PC, Piehler JM, Trastek VF, Payne WS, Bernatz PE. Pulmonary aspergilloma: results of surgical treatment. J Thorac Cardiovasc Surg. 1986;92:981-8.
Belcher J, Plummer N. Surgery in broncho-pulmonary aspergillosis. Br J Dis Chest. 1960;54:335-41.
Kibbler CC, Milkins SR, Bhamra A, Spiteri MA, Noone P, Prentice HG. Apparent pulmonary mycetoma following invasive aspergillosis in neutropenic patients. Thorax. 1988;43:102-12.
Binder RE, Faling LJ, Pugatch RD, Mahasen C, Snider GL. Chronic necrotizing pulmonary aspergillosis: a distinct entity. Med. 1982;61:109-24.
Lee SH, Lee BJ, Jung do Y, Kim JH, Sohn DS, Shin JW, et al. Clinical manifestations and treatment outcomes of pulmonary aspergilloma. Korean J Intern Med. 2004;19:38-42.
Kim YT, Kang MC, Sung SW, Kim JH. Good long-term outcomes after surgical treatment of simple and complex pulmonary aspergilloma. Ann Thorac Surg 2005;79:294-8.
Regnard JF, Sacrd P, Nicolosi M, Spagiarri L, Magdeleinat P, Jauffret B, et al. Aspergilloma: a series of 89 surgical cases. Ann Thorac Surg. 2000;69:898-903.
Park CK, Theon S. Results of surgical treatment for pulmonary aspergilloma. Eur J Cardiothorac Surg. 2002;21:918-23.
Babatasi G, Massetti M, Chapelier A, Fadel E, Macchiarini P, Khayat A, et al. Surgical treatment of pulmonary aspergilloma: current outcome. J Thorac Cardiovasc Surg. 2000;119:906-12.
Oakley R, Petrou M, Goldstraw P. Indications and outcome of surgery for aspergilloma. Thorax. 1997;52:813-5.
Kay PH. Surgical management of pulmonary aspergilloma. Thorax. 1997;52:753-4.
Judson MA, Stevens DA. The treatment of pulmonary aspergillomas. Curr Opin Investig Drugs. 2001;2:1375-7.
Akbari JG, Varma PK, Neema PK, Menon MU, Neelakandhan KS. Clinical profile and surgical outcome for pulmonary aspergilloma: a single center experience. Ann Thorac Surg. 2005;80:1067-72.
Henderson RD, Deslauries J, Ritcey EL, Delarue NC, Pearson FG. Surgery in pulmonary aspergillosis. J Thorac Cardiovasc Surg. 1975;70:1088-92.
