Digital gangrene in patients with sepsis

Archana A. Nema, Jitendra R. Darshan, Saumya Iyer


Background: Symmetrical peripheral gangrene is a rare condition seen in patients of severe sepsis with hypotension. Gangrene is of dry type, limited to the digits only with all peripheral pulses palpable.  

Methods: Seven patients of severe sepsis with various etiologies were admitted in surgical ICU. These patients developed symmetrical peripheral gangrene during their stay in SICU at a variable period. Detailed history and case records were studied, and data was analyzed. Review of literature was done and compared with findings of our cases.  Results: All seven patients had severe sepsis with disseminated intravascular coagulation and all seven required ventillatory support. Administration of inotropes increased the pace of ischemic process.  

Conclusions: Anticipation and prompt recognition of this condition can limit the progress of gangrene. Treatment is emphasized on the primary condition with focus on limiting the gangrene by local procedures.  


Gangrene, Necrosis, Sepsis, Symmetrical peripheral gangrene

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