A hospital based clinical study of 100 patients of solitary thyroid nodule
DOI:
https://doi.org/10.18203/2349-2902.isj20180052Keywords:
Neck swelling, Solitary nodule, Thyroid, Thyroid neoplasmAbstract
Background: Thyroid nodules present as a challenge in their diagnosis, evaluation and management. Often these lumps are large in size and develop at the edge of thyroid gland so that they are felt or seen as a lump in front of the neck. The prevalence of these nodules in a given population depends on number of factors like age, sex, diet, iodine deficiency and even therapeutic and environmental radiation exposure. Prevalence increases with age with spontaneous nodules occurring at a rate of 0-0.8% per year, beginning early in life and extending till the eighth decade. In this study, the basic aim is to depict the various clinical presentations of solitary thyroid nodule and thereby find out the best diagnostic modality so as to plan out the most effective treatment strategy for such lesions.
Methods: A hospital based prospective study was done with 100 patients to assess the various clinical presentations of solitary thyroid nodule and thereby find out the best diagnostic modality so as to plan out the most effective treatment strategy for such lesions.
Results: Thyroid nodules are common in females of age group 31-40 years. Commonest presenting complaint is swelling in the front of lower neck. Most of the patients presented between 6 months to 3 years of onset of swelling.
Conclusions: In present study, the sensitivity and specificity of FNAC was 85.71% and 100% respectively. All malignant lesions on FNAC were confirmed by histopathology indicating its excellence. Therefore, FNAC helps in planning the correct management and avoids second surgery.
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References
Krukowski ZH. The thyroid and the thyroglossal tract. Chapter 53 in Bailey and Love’s short practice of Surgery, 24th Ed. NS Pubished by Chapman and Hall Medical. London; 2000:707-733.
Ananthkrishnan N. the single thyroid nodule - A South Indian Profile of 503 Patients with special Reference to Incidence of Malignancy. Ind J Surg. 1993;55(10):487-92.
Cole WH, Majarakis JD. Incidence of carcinoma of the thyroid in nodular goitre. J Clin Endocrinol. 1949;9:1007-11.
Ezzat S, Sarti DA, Cain DR, Braunstein GD. Thyroid incidentalomas, prevalence by palpation and ultrasonography. Arch Intern Med. 1994;154:1838-40.
Maddox PR, Malcolm H, Wheeler MD. Approach to thyroid nodules. Chapter 9, textbook of Endocrine Surgery, Orlo H. Clark, Philadelphia, WB Saunders; 1997:688.
Mazzaferri EL. Management of solitary thyroid nodule. N Engl J Med. 1993;328:553-9.
Neki NS, Kazal HL. Solitary Thyroid Nodule- An Insight. JIACM. 2006;7(4):328-33.
Tai JD, Yang JL, Wu SC, Wang BW, Chang CJ. Risk factors for malignancy in patients with solitary thyroid nodules and their impact on the management. J Cancer Res Ther. 2012;8:379-83.
Unnikrishnan AG, Kalra S, Baruah M, Nair G, Nair V, Bantwal G, et al. Endocrine Society of India management guidelines for patients with thyroid nodules: A position statement. Indian J Endocrinol Metab. 2011;15:2-8.
Gupta M, Gupta S, Gupta VB. Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. J Thyroid Res. 2010;2010:379051.
Iqbal M, Mehmood Z, Rasul S, Inamullah H, Shah SS, Bokhari I. Carcinoma thyroid in multi and uninodular goiter. J Coll Physicians Surg Pak. 2010;20:310-2.
Delbridge L. Solitary thyroid nodule: Current management. ANZ J Surg. 2006;76:381-6.
Lida F. Thyroid Carcinoma. World J Surg. 2007;45(4).
Sherma SI. Thyroid carcinoma. Lancet. 2003;361:501-11.
Priyadarshi N, Mistry D, Kharadi N. Study of Management of Solitary Thyroid Nodule. Int J Sci Res. 2013;2(3).