Fine needle aspiration cytology (FNAC) in pre-operative diagnosis of breast lesions in Kadapa region of Andhra Pradesh, India

Chakarala Obula Reddy; Garisa Chandra Mohana Reddy

doi:10.18203/2349-2902.isj20175411

Authors

Chakarala Obula Reddy Department of Surgery, Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh-516003, India
Garisa Chandra Mohana Reddy Department of Surgery, Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh-516003, India

DOI:

https://doi.org/10.18203/2349-2902.isj20175411

Keywords:

Aspiration, Breast, Cytology, Fine needle

Abstract

Background: Various diagnostic methods have been developed to evaluate the palpable and non-palpable breast lesions, but Fine needle aspiration cytology of the palpable breast masses have become increasingly popular as a diagnostic technique to assess the breast lesions. To study the role of FNAC in diagnosis of breast lumps.

Methods: 60 female patients (11-74 years age group) with palpable breast lump were utilized to study the role of Fine needle aspiration cytology for clinically palpable breast lump was carried out in Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh.

Results: Fine needle aspiration cytology revealed benign in 22 patients, suspicious in 3 and 35 malignant lesions were 93.10% with false negative rate of 6.9% and false positive rate of 0%. The overall sensitivity of fine needle aspiration cytology in diagnosing the palpable breast lump in our study was 93.10%, specificity was 100%, positive predictive of 100% and negative predictive value of 90.47%.

Conclusions: FNAC is easy to perform and painless procedure and standard tool for diagnosis of breast lumps with high percentage of true positives without virtual complications.

Metrics

Metrics Loading ...

References

Duguid HL, Wood RA, Irving AD, Preece PE, Cuschieri A. Needle aspiration of the breast with immediate reporting of material. Br Med J. 1979;2:185-7.

Kline TS, Joshi LP, Neal HS. Fine-needle aspiration of the breast: Diagnoses and pitfalls. A review of 3545 cases. Cancer. 1979;44:1458-64.

Tiwari M. Role of fine needle aspiration cytology indiagnosis of breast lumps. Kathmandu Univ Med J (KUMJ). 2007;5:215-7.

Saxe A, Phillips E, Orfanou P, Husain M. Role of sample adequacy in fine needle aspiration biopsy of palpable breast lesions. Am J Surg. 2001;182:369-71.

Yeoh GPS, Chan KW. Fine-needle aspiration of breast masses: an analysis of 1533 cases in private practice. Hong Kong Med J. 1998;4:283-7.

Patel JJ, Gartell PC, Guyer APB, Herbert A, Taylor I. Use of ultrasound localization to improve results of fine needle aspiration cytology of breast masses. J R Soc Med. 1988;81:10-12.

Padel AF, Coghill SB, Powis SJ. Evidence that sensitivity is increased and the inadequacy rate decreased when pathologists take aspirates for cytodiagnosis. Cytopathology. 1993;4:161-5.

Cohen MB, Rodgers RP, Hates MS, Gonzales JM, Ljung BM, Beckstead JH. Influence of training and experience in fine-needle aspiration biopsy in breast. Receiver operating characteristic curve analysis. Arch Pathol Lab Med. 1987;111:518-20.

Ljung BM, Drejet A, Chiampi N, Jeffrey J, Goodson WH, Chew K. Diagnostic accuracy of fine needle aspiration biopsy is determined by physician training in sampling technique. Cancer. 2001;93:263-8.

Bibbo M, Abati A, Ferenczy A, Robitaille J, Franco E, Arseneau J, Richart RM, Wright TC, Elsheikh TM, Bernacki EG, Burch HB. The uniform approach to breast fine needle aspiration biopsy. Acta Cytologica. 1996;40(6):1120-6.

Dixon JM, Anderson TJ, Lamb J, Nixon SJ, Forrest AP. Fine needle aspiration cytology, in relationships to clinical examination and mammography in the diagnosis of a solid breast mass. Br J Surg. 1984;71:593-6.

Homesh NA, Issa MA, El-Sofiani HA. The diagnostic accuracy of fine needle aspiration cytology versus core needle biopsy for palpable breast lump(s). Saudi Med J. 2005;26:42-6.

Ariga R, Bloom K, Reddy VB, Kluskens L, Francescatti D, Dowlat K, et al. Fine needle aspiration of clinically suspicious palpable breast mass with histopathological correlation. American Journal of Surgery. 2002;184:410-13.