Effectiveness of conservative management of acute fissure in ano: a prospective clinical study of 165 patients

Authors

  • Sajith Babu S. M. Department of Surgery, Shyam Shah Medical College, Rewa, Madhya Pradesh, India http://orcid.org/0000-0003-4012-5724
  • Rachna Gupta Department of Surgery, Shyam Shah Medical College, Rewa, Madhya Pradesh, India
  • Lalmani Singh Department of Surgery, Shyam Shah Medical College, Rewa, Madhya Pradesh, India

DOI:

https://doi.org/10.18203/2349-2902.isj20173881

Keywords:

Acute fissure in ano, Dietery fibre, Diltiazem ointment, Sitz bath

Abstract

Background: Fissure-in-ano is a common yet troublesome condition; if acute, the severity of patient discomfort and extent of disability far exceed that would be expected from a seemingly trivial lesion. The present study was carried out to study the effectiveness of conservative management in symptom relief in acute fissure in ano.

Methods: The study was conducted in 165 patients with acute fissure in ano attending Surgery OPD and/or admitted in surgical wards of Sanjay Gandhi Memorial Hospital associated with Shyam Shah Medical College, Rewa during the period from 1st August 2015 to 31st July 2016. It was a prospective clinical study. All the study subjects underwent extensive clinical examination and were prescribed conservative treatment regime. Follow up was done at the end of 2 weeks, 4 weeks and 6 weeks and the data was analyzed. 165 patients diagnosed as having acute fissure in ano. The outcome was assessed based on the following parameters; symptomatic relief, pain relief based on visual analogue scale and healing of ulcer.

Results: Most of the patients were young adults with a slight female dominance. Pain during defecation and bleeding per rectum were the major presenting complaints. 73.94% of patients achieved symptom relief within 2 weeks of conservative treatment. At 6 weeks follow up after giving conservative line of management, 97.58% achieved symptom relief with healing of ulcer. Mean pain score was reduced from 9.5±0.71 at the start of therapy to 1.33±0.69 at the end of 6 weeks of conservative therapy.

Conclusions: Acute fissure in ano can be easily cured with systematic usage of conservative treatment regime. A proper follow up along with patient education can help to achieve good remission and avoid unnecessary surgical intervention.

Metrics

Metrics Loading ...

References

Michael E, Friscia MD, Robert D. Anal pain: office diagnosis and treatment 2008;48:1-3.

Steven D. Wexener, pruritus ani and anal fissure (18). In: David E Beck and David R Welling. Editor. Patient Care In Colorectal Surgery, 2nd edition; 1991:243-54.

Hananel N, Gordon PH. Re-examination of clinical manifestations and response to therapy of fissure-in-ano. Dis Colon Rectum. 1997;40(2):229-33.

Notaras MJ. The treatment of anal fissure by lateral subcutaneous internal sphincterotomy: a technique and results. Br J Surg. 1971;58(2):96-100.

Bullard KM, Rothenberger DA. Colon, rectum and anus. Shwartz’s Principles of Surgery; 2005;8:28-1104.

McNamara MJ, Percy JP, Fielding IR. A manometric study of anal fissure treated by subcutaneous lateral internal sphincterotomy. Ann Surg. 1990;211(2):235-8.

Eisenhammer S. The evaluation of the internal anal sphincterotomy operation with special reference to anal fissure. Surg Gynecol Obstet. 1959;109:583.

Jensen SL. Treatment of first episode of acute anal fissure - a prospective, randomized study of lignocaine ointment versus hydrocortisone ointment versus warm Sitz bath plus bran. BMJ. 1986;292(6529):1167-9.

Raj VK, Kadam MM. A study on different modalities in management of fissure in ano. Int J Sci Res. 2014;3(10):942-8.

Giridhar CM, Babu P, Rao KS. A comparative study of lateral sphincterotomy and 2% diltiazem gel local application in the treatment of chronic fissure in ano. J Clin Diag Res: JCDR. 2014;8(10):NC01.

Kuiri SS, Saha AK, Mandal N, Ganguly SS. Comparative study of lateral sphincterotomy versus local 2 % Diltiazem ointment for the treatment of chronic anal fissure. IOSR-JDMS. 2014;13(6):36-40.

Jensen SL. Diet and other risk factors for fissure-in-ano. Prospective case control study. Dis Colon Rectum. 1988;31(10):770-3.

Gupta PJ. Consumption of red-hot chili pepper increases symptoms in patients with acute anal fissures. A prospective, randomized, placebo-controlled, double blind, crossover trial. Arq Gastroenterol. 2008;45:124-7.

Choudhary A, Katti P, Prasad KK. Comparative study of topical diltiazem sphincterotomy and lateral internal sphincterotomy in the treatment of chronic fissure-in-ano: a prospective analytical study. Sch J App Med Sci. 2016;4(4D):1402-5.

Khubchandani IT, Reed JF. Sequelae of internal sphincterotomy for chronic fissure in ano. Br J Surg. 1989;76:431-4.

Lock MR, Thompson JPS. Fissure in Ano. The initial management and prognosis. BTS. 1977;64:355-8.

Lund JN, Scholefield JH. A randomized, prospective, double-blind, placebo controlled trial of glyceryl trinitrate ointment in treatment of anal fissure. Lancet. 1997;9044(349):11-14.

Tayfun YA, Dogan GB, Mahmut OC, Ferda NKB, Sibel GOD, Omer A. Comparison of controlled-intermittent anal dilatation and lateral internal sphincterotomy in the treatment of chronic anal fissures: A prospective, randomized study. Int J Surg. 2009;7:228-31.

Comparative study of oral and topical nifedipine in the treatment of chronic anal fissure. Sudanese J Pub Health. 2010;5(4):1523-8.

Lund JN, Scholefield JH. Aetiology and treatment of anal fissure. Br J Surg. 1996;83(10):1335-44.

Schouten WR, Briel JW, Auwerda JJ. Relationship between anal pressure and anodermal blood flow. The vascular pathogenesis of anal fissures. Diseases of the Colon and Rectum. 1994;37(7):664-9.

McDonald P, Driscoll AM, Nicholls RJ. The anal dilator in the conservative management of acute anal fissures. Br J Surg. 1983;70:25-6.

Gupta P. Randomized, controlled study comparing sitz-bath and no-sitz-bath treatments in patients with acute anal fissures. ANZ J Surg. 2006;76:718-21.

Gough MJ, Lewis A. The conservative treatment of fissure-in-ano. Br J Surg. 1983;70(3):175-6.

Goligher JC. Surgery of anus, rectum, and colon. 4th ed. London: Balliere, Tindall; 1980:946.

Antropoli C, Perrotti P, Rubino M, Martino A, De Stefano G, Migliore G, et al. Nifedipine for local use in conservative treatment of anal fissures. Dis Colon Rectum. 1999;42(8):1011-5.

Gagliardi G, Pascariello A, Altomare DF, Arcanà F, Cafaro D, La Torre F, et al. Optimal treatment duration of glyceryl trinitrate for chronic anal fissure: results of a prospective randomized multicenter trial. Techniques in Coloproctol. 2010;14(3):241-8.

Golfam F, Golfam P, Golfam B, Pahlevani P. Comparison of topical nifedipine with oral nifedipine for treatment of anal fissure: a randomized controlled trial. Iran Red Crescent Med J. 2014;16(8):e13592.

Shub HA, Salvati EP, Rubin RJ. Conservative treatment of anal fissure: an unselected, retrospective and continuous study. Dis Colon and Rectum. 1978;21(8):582-3.

Merenstein D, Rosenbaum D. Is topical nifedipine effective for chronic anal fissures?. J Family Practice. 2003;52(3):190-2.

Slawson D. Topical nifedipine plus lidocaine gel effective for anal fissures. Am Family Phy. 2003;67(8):1781.

Downloads

Published

2017-08-24

How to Cite

S. M., S. B., Gupta, R., & Singh, L. (2017). Effectiveness of conservative management of acute fissure in ano: a prospective clinical study of 165 patients. International Surgery Journal, 4(9), 3028–3033. https://doi.org/10.18203/2349-2902.isj20173881

Issue

Section

Original Research Articles