Clinical study on fibroadenoma of the breast

Purushothaman Rangaswamy, Shaikh Afzal Rubby


Background: It is a benign encapsulated tumour occurring commonly in young females of 15 -25 years of age. Presently it is considered as hyperplasia of a single lobule of the breast (classified under ANDI). Fibro-adenomas are one of the main benign diseases of breast. Though considered as a risk factor for development of breast cancer its reporting has been over shadowed by that of breast cancer.

Methods: The study was undertaken during the period August 2014 to August 2016, patients who attended surgical outpatient as well as in patient of ESIC medical college hospital formed part of the study.

Results: During the study period a total of 80 cases were confirmed as fibro-adenoma. The ages of cases ranged from 10-60yrs maximum number of cases 50 (62.5%) was in age group 16-30 years followed by 31 - 45 years with mean age of presentation 27 years. Majority of cases 60 (75.0%) belonged to urban background. It was found that 55 (68.75%) of the cases were married.

Conclusions: Fibro-adenomas which is small, single, age <30 years can be left alone with regular follow - up with USG at 6 monthly interval. But anxiousness of patient and parents find difficult for this conservative approach.


Benign breast disease, Breast cancer, Mastalgia,Fibro-adenosis,Fibro-adenoma

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Rangabashyam N, Gnanaprakasan D, Krishnaraj B, Manohar V, Vijayalakshmi SR. Spectrum of benign breast lesions in Madras. J Royal College Surg Edinburgh. 1983;28:369-73.

Dent DM, Hacking EA, Wilkie W. Benign breast disease clinical classification and disease distribution. British J General Pract. 1980;42(suppl 56):69-71.

Franyz VK, Pickern JW, Melcher GW, Auchincoloss JR. Incidence of chronic cystic disease in so-called normal breast: a study based on 225 post mortem examinations. Cancer. 1951;4:762-7.

Hanna R, Ashebu S. Giant fibroadenoma of the breast in an Arab population. Australasian Radiology. 2002;46:252-6.

Stehr KG, Lebeau A, Stehr M, Grantzow R. Fibroadenoma of the breast in an 11-year-old girl. European J Pediat Surg. 2004;14(1):56-9.

Amshel CE, Sibley E. Multiple unilateral fibroadenomas. Breast J. 2001;7(3):189-91.

Soini I, Aine R, Lauslthti K. Independent risk factor of benign and malignant breast lesion. American J Epidemiol. 1981;114:507-14.

Williamson ME, Lyons K, Hyghes LE. Multiple fibroadenoma of the breast a problem of uncertain incidence and management. Annals Royal College Surg England. 1993;75:161-3.

Ravnihar B, Segel DG, Lindther J. An epidemiologic study of breast cancer and benign breast neoplasm in relation to the oral contraceptive and estrogen use. European J Cancer. 1979;15:395-405.

Canny PF, Berkowitz GS, Kelsey JL. Fibroadenoma and the use of exogenous hormones: a case control study. American J Epidemiol. 1988;127:454-61.

Foster ME, Garrahan N, Williams S. Fibroadenoma of the breast: a clinical and pathological study. J Royal College Surg Edinburgh. 1988;33:13-6.

Houssami N, Cheung MN, Dixon JM. Fibroadenoma of the breast. Medical Journal of Australia. 2001;174(4):185-8.

Ajao OG. Benign Breast Lesions. Journal of the National Medical Association. 1979;71(9):786-9.

Onuigb WIB. Adolescent mass in Nigerian igbos. American Journal of Surgery. 1979;137:367-71.

Schuerch C, Rosen PP, Hirota T, Itabashi M. A pathologic study of benign breast disease in Tokyo and New York. Cancer. 1982;50:1899-902.

Greenblatt RB, Nezhat C, Ben-Nun I. The treatment of benign breast disease with danazol. Fertility and Sterility. 1980;34(3):242-5.

Ranieri E, Barberi S, Caprio G. Diagnosis and treatment of fibroadenoma of the breast: 20 years’ experience. Chirurgia italiana. 2006;58(3):295-7.

Dixon JM, Dobie V, Lamb J. Assessment of the acceptability of mconservative management of fibroadenoma of the breast. British J Surg. 1996;83(2):264-5.

Alle KM, Moss J, Venegas RJ. Conservative management of fibroadenoma of the breast. British J Surg. 1996;83(7):992-3.

Liu XF. A clinical study on the resection of breast fibroadenoma using two types of incision. Scandinavian J Surg. 2011;100:147-52.

Ahmed HG, Ali AS, Almobarak AO. Frequency of breast cancer among Sudanese patients with breast palpable lumps. Indian J Cancer. 2010;47:23-6.