Imaging and cytopathological correlation of space occupying lesions in liver: a prospective observational study

Authors

  • Sachinkumar Patel Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India
  • P. B. Nichkaode Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India
  • Prasad Y. Bansod Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India http://orcid.org/0000-0001-8686-1925
  • Murtaza Akhtar Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India

DOI:

https://doi.org/10.18203/2349-2902.isj20171622

Keywords:

Benign liver lesions, Liver abscess, Liver imaging, Liver cytology, Malignant liver lesions, Space occupying lesion

Abstract

Background: Liver is a common site for Space occupying lesions. It is difficult to distinguish these entities with imaging criteria alone. Development in liver surgery and liver pathology have led to many new types of primary hepatic space-occupying lesions (PHSOLS) being surgically resected and pathologically diagnosed, which has greatly increased the surgicopathological spectrum of PHSOLS.

Methods: A 2-year tertiary care teaching hospital based longitudinal study with 77 participants was done. Selection criteria was defined and a prestructured proforma was made to assess and note the findings.

Results: The mean age of occurrence of space occupying lesions of liver was 45.49±13.45 years with a range of 24 to 70 years. Space occupying lesions of liver was commonly observed in 4th Decade of life. 64.93% pathology of Space Occupying Lesions of Liver occur in males. 76.62% patients of space occupying lesions of liver present with pain in right upper quadrant.

Conclusions: Majority of space occupying lesions were surgically managed with a short-term follow-up of 1 month in which no complications were noted.

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Author Biographies

Sachinkumar Patel, Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India

Junior resident, Department of surgery

P. B. Nichkaode, Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India

Associate Professor

Prasad Y. Bansod, Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India

Senior Resident, Department of Surgery

Murtaza Akhtar, Department of Surgery, NKP Salve Institute of medical sciences, Nagpur, Maharashtra, India

Prof & HOD department od surgery

References

Jarnagin WR, Blumgart LH. Blumgart's surgery of the liver, biliary tract, and pancreas. Elsevier Saunders. 2012.

Tchelepi H, Ralls PW. Ultrasound of focal liver masses. Ultrasound quarterly. 2004;20(4):155-69.

Standring S, Ellis H, Healy J, Johnson D, Williams A, Collins P, Wigley C. Gray's Anatomy: The anatomical basis of clinical practice. Am J Neuroradiol. 2005;26(10):2703.

Sherlock S, Dooley J. Diseases of the liver and biliary system. John Wiley and Sons; 2008.

Sutherland F, Harris J. Claude couinaud: a passion for the liver. Arc Surg. 2002;137(11):1305-10.

Scanlon VC, Sanders T. Essentials of anatomy and physiology. FA Davis; 2014.

Bryan PJ, Martin Dinn W, Grossman ZD, Wistow BW, McAfee JG, Kieffer SA. Correlation of computed tomography, gray scale ultrasonography, and radionuclide imaging of the liver in detecting space-occupying processes. Radiol. 1977;124(2):387-93.

Feldman M, Friedman LS, Brandt LJ. Sleisenger and Fordtran's gastrointestinal and liver disease: pathophysiology, diagnosis, management, expert consult premium edition-enhanced online features. Elsevier Health Sciences; 2010.

Kaltenbach TE, Engler P, Kratzer W, Oeztuerk S, Seufferlein T, Haenle MM, et al. Prevalence of benign focal liver lesions: ultrasound investigation of 45,319 hospital patients. Abdom Radiol. 2016;41(1):25-32.

Tocchi A, Mazzoni G, Costa G, Cassini D, Bettelli E, Agostini N, et al. Symptomatic nonparasitic hepatic cysts: options for and results of surgical management. Arc Surg. 2002;137(2):154-8.

Cowles RA, Mulholland MW. Solitary hepatic cysts. J Am Col Surg. 2000;191(3):311-21.

Akther MJ, Khanam N, Rao S. Clinico epidemiological profile of hydatid diseases in central india, a retrospective and prospective study. Int J Biol Med Res. 2011;2(3):603-6.

Palanivelu C, Jani K, Malladi V, Senthilkumar R, Rajan PS, Sendhilkumar K, et al. Laparoscopic management of hepatic hydatid disease. J Society Laparoendosco Surg. 2006;10(1):56-62.

Daradkeh S, Husam EM, Farah G, Sroujieh AS, Abu-Khalaf M. Predictors of morbidity and mortality in the surgical management of hydatid cyst of the liver. Langenbeck's Arch Surg. 2007;392(1):35-9.

DeBAKEY ME, Ochsner A. Hepatic amebiasis; a 20-year experience and analysis of 263 cases. Surg Gynecol Obstetr. 1951;92(3):209.

Mathur S, Gehlot RS, Mohta A, Bhargava N. Clinical profile of amoebic liver abscess. J Indian Acad Clin Med. 2002;3:367-73.

Ramani A, Ramani R, Shivananda PG. Amoebic liver abscess. a prospective study of 200 cases in a rural referral hospital in South India. Bahrain Medical Bulletin. 1995;17(4).

Blumgart LH. Amoebic liver abscess. OP Kapoor. 286× 220 mm. with 271 illustrations. Bombay: SS Publishers (16 Rajat, Mount Pleasant Road, Bombay 400006). $50 or Rs. 425; 1979:205.

Schwerk WB, Schmitz‐Moormann P. ultrasonically guided fine‐needle biopsies in neoplastic liver disease: Cytohistologic diagnoses and echo pattern of lesions. Cancer. 1981;48(6):1469-77.

Pinnamaneni HB, Shukla AK, Krishnappa N. Sonographic evaluation of focal and diffuse hepatic lesions. J Evol Med Dent Sci. 2014;3(45):11114-29.

Thimmaiah VT. Evaluation of focal liver lesions by ultrasound as a prime imaging modality, Sch J App Med Sci ed. 2013;1(6):1041-59.

Sánchez AJ, Barberena IJ, Sauras HM, Jiménez MF, Pérez GC, Carrillo DA. Computerized axial tomography, ultrasonography and percutaneous drainage in the diagnosis and treatment of pyogenic abscess of the liver. Revista de Med de la Universidad de Navarra. 1987;32(3):139-42.

Donovan AJ, Yellin AE, Ralls PW. Hepatic abscess. World J Surg. 1991;15(2):162-9.

Roy SK, Sultana S, Mollah NU, Yasmin T, Sarker A, uz Jahan M. Role of ultrasonography in diagnosis of solid space occupying lesion in the liver correlation with FNAC. Bangladesh Med Res Coun Bullet. 2016;41(2):81-8.

Snow JH, Goldstein HM, Wallace S. Comparison of scintigraphy, sonography, and computed tomography in the evaluation of hepatic neoplasms. Am J Roentgenol. 1979;132(6):915-8.

Nelson RC, Chezmar JL, Sugarbaker PH, Bernardino ME. Hepatic tumors: comparison of CT during arterial portography, delayed CT, and MR imaging for preoperative evaluation. Radiol. 1989;172(1):27-34.

Kinkel K, Lu Y, Both M, Warren RS, Thoeni RF. Detection of hepatic metastases from cancers of the gastrointestinal tract by using noninvasive imaging methods (US, CT, MR imaging, PET): a meta-analysis. Radiol. 2002;224(3):748-56.

Choi J. Imaging of hepatic metastases. Cancer Control. 2006;13(1):6.

Chezmar JL, Rumancik WM, Megibow AJ, Hulnick DH, Nelson RC, Bernardino ME. Liver and abdominal screening in patients with cancer: CT versus MR imaging. Radiol. 1988;168(1):43-7.

Dietrick RB. Experience with liver abscess. Am J Surg. 1984;147(2):288-91.

Gupta SS, Singh O, Sabharwal G, Hastir A. Catheter drainage versus needle aspiration in management of large (> 10 cm diameter) amoebic liver abscesses. ANZ J Surg. 2011;81(7‐8):547-51.

Singh S, Chaudhary P, Saxena N, Khandelwal S, Poddar DD, Biswal UC. Treatment of liver abscess: prospective randomized comparison of catheter drainage and needle aspiration. Ann Gastroenterol. 2013;26(4):332.

Saraswat VA, Agarwal DK, Baijal SS, Roy S, Choudhuri G, Dhiman RK, et al. Percutaneous catheter drainage of amoebic liver abscess. Clin Radiol. 1992;45(3):187-9.

Agarwal DK, Baijal SS, Roy S, Mittal BR, Gupta R, Choudhuri G. Percutaneous catheter drainage of amebic liver abscesses with and without intrahepatic biliary communication: a comparative study. Eur J Radiol. 1995;20(1):61-4.

Baek SY, Lee MG, Cho KS, Lee SC, Sung KB, Auh YH. Therapeutic percutaneous aspiration of hepatic abscesses: effectiveness in 25 patients. AJR. Am J Roentgenol. 1993;160(4):799-80.

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Published

2017-04-22

How to Cite

Patel, S., Nichkaode, P. B., Bansod, P. Y., & Akhtar, M. (2017). Imaging and cytopathological correlation of space occupying lesions in liver: a prospective observational study. International Surgery Journal, 4(5), 1687–1696. https://doi.org/10.18203/2349-2902.isj20171622

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Original Research Articles