Colonic intussusception caused by a giant colonic lipoma: case report and literature review
DOI:
https://doi.org/10.18203/2349-2902.isj20260855Keywords:
Colonic lipoma, Intussusception, Bowel obstruction, Colectomy, Colorectal surgeryAbstract
Colonic lipomas are rare benign tumours that frequently remain asymptomatic. However, when large in size, they may cause serious complications such as intussusception and bowel obstruction, challenging differentiation from malignant neoplasms. This paper reports the case of a 54-year-old male patient admitted to the emergency department with intermittent abdominal pain and progressive constipation over two months. Computed tomography revealed colo-colonic intussusception involving the descending and sigmoid colon with a 4.2 cm endoluminal lesion suggestive of neoplasia. Colonoscopy confirmed a pedunculated stenotic mass, enabling intussusception reduction, but diagnostic biopsy was not feasible. Due to persistent obstructive symptoms, inability to exclude malignancy, and risk of recurrent intussusception, left colectomy via laparotomy was performed. Pathological examination confirmed a benign submucosal lipoma measuring 4.2×3.5×3.5 cm without signs of malignancy. Postoperative course was uneventful with progressive bowel recovery and hospital discharge in good clinical condition. This report emphasizes the importance of accurate differential diagnosis of colonic lipomas, judicious indication for surgical resection in complicated giant lipomas, and minimally invasive techniques available for management of this condition.
Metrics
References
Nallamothu G, Adler DG. Large colonic lipomas. Gastroenterology and Hepatology. 2011;7(7):490-2.
Tasselli FM, Urraro F, Sciaudone G, Bagaglini G, Pagliuca F, Reginelli A, et al. Colonic lipoma causing bowel intussusception: an up-to-date systematic review. J Clin Med. 2021;10(21):5149. DOI: https://doi.org/10.3390/jcm10215149
Vagholkar K, Bendre M. Lipomas of the colon: a surgical challenge. Int J Clin Med. 2014;2014:301523. DOI: https://doi.org/10.4236/ijcm.2014.56046
Lee JM, Kim JH, Kim M, Kim JH, Lee YB, Lee JH, et al. Endoscopic submucosal dissection of a large colonic lipoma: report of two cases. World J Gastroenterol. 2015;21(10):3127-31. DOI: https://doi.org/10.3748/wjg.v21.i10.3127
Moreno-Monteagudo JA, Martín‑Domínguez V, Santander C. Giant colon lipoma complicated with intussusception and low digestive hemorragy. Gastroenterología y Hepatología. 2020;44(2):126-8. DOI: https://doi.org/10.1016/j.gastre.2020.05.014
Oliveira IAN, Mesquita HC, Santiago RR, Bandeira JAG, Matos MF, Guerra JC, et al. Lipoma de intestino grosso. Revista Brasileira de Coloproctologia. 2003;23(1):28-9.
Aytac B, Yercı Ö, Gürel S, Ferik Z. Colonic lipomas mimicking colon cancer. Turk J Pathol. 2010;26(3):196-9. DOI: https://doi.org/10.5146/tjpath.2010.01024
Gould DJ, Morrison CA, Liscum KR, Silberfein EJ. A lipoma of the transverse colon causing intermittent obstruction: a rare cause for surgical intervention. World J Gastroenterol. 2011;7(7):487-90.
Bronswijk, M., Vandenbroucke, A. M., & Bossuyt, P. Endoscopic treatment of large symptomatic colon lipomas: A systematic review of efficacy and safety. Un Eur Gastroenterol J. 2020;8(10):1147-54. DOI: https://doi.org/10.1177/2050640620948661
Erginoz E, Uludag SS, Cavus GH, Zengin K, Ozcelik MF. Clinicopathological features and management of colonic lipomas. Medicine. 2022;101(10):e29004. DOI: https://doi.org/10.1097/MD.0000000000029004
Kyawzaw K, Ofori E, Sandar L, Naing LA, Madhavi R. Pillow sign in colonoscopy. MOJ Clin and Med Case Rep. 2018;8(2):57-8. DOI: https://doi.org/10.15406/mojcr.2018.08.00240
De Beer RA, Shinya H. Colonic lipomas: an endoscopic analysis. Gastrointest Endosc. 1975;22(2):90-1. DOI: https://doi.org/10.1016/S0016-5107(75)73710-0
Agrawal A, Singh KJ. Symptomatic intestinal lipomas: our experience. Med J Armed Forces India. 2011;67(4):374-6. DOI: https://doi.org/10.1016/S0377-1237(11)60090-7
Roknsharifi S, Ricci Z, Kobi M, Huo E, Yee J. Colonic lipomas revisited on CT colonography. Abdom Radiol. 2022;47(5):1788-97. DOI: https://doi.org/10.1007/s00261-022-03489-2
Sapalidis K, Laskou S, Kosmidis C, Anthimidis G, Spartalis E, Koimtzis G, et al. Symptomatic colonic lipomas: report of two cases and a review of the literature. SAGE Open Med Case Rep. 2019;7:2050313X19830477. DOI: https://doi.org/10.1177/2050313X19830477
Bagherzade G, Etemad O. Recto-sigmoid lipoma: a case report and review of the literature. J Coloproctol. 2017;37(1):50-4. DOI: https://doi.org/10.1016/j.jcol.2016.06.003
Zhou XC, Hu KQ, Jiang Y. A 4-cm lipoma of the transverse colon causing colonic intussusception: a case report and literature review. Oncol Lett. 2014;8(3):1090-2. DOI: https://doi.org/10.3892/ol.2014.2278
Thompson WM. Imaging and findings of lipomas of the gastrointestinal tract. Am J Roentgenol. 2005;184(4):1163-71. DOI: https://doi.org/10.2214/ajr.184.4.01841163
Magalhães MJ, Albuquerque A, Carvalho A, Macedo G. A rare case of colonic pseudolipomatosis. Ann Gastroenterol. 2015;28(1):146-7.
Caliskan A, Goyal A, Bhattacharya B, Sirohi D, Xue Y, Liu X. Intramucosal lipomas of the colon implicate Cowden syndrome. Mod Pathol. 2018;31(4):643-51. DOI: https://doi.org/10.1038/modpathol.2017.161
Bouzid A, Belhadj A, Khefacha F, Touati MD, Saidani A, Chebbi F. A laparoscopic odyssey: managing giant colonic lipoma-induced colo-colonic intussusception: a case report. Int J Surg Case Rep. 2024;119:109780. DOI: https://doi.org/10.1016/j.ijscr.2024.109780
Prien C, Riaz M, Hamid M, Nisar M, Javed A. Management options of giant colonic lipomas. Cureus. 2022;14(3):e22341. DOI: https://doi.org/10.7759/cureus.23370
Haider S, Aslan F, Kang Y, Paladini A, Coyle WJ. Loop-and-let-go technique for the management of symptomatic large colonic lipoma. VideoGIE. 2023;8(8):325-7. DOI: https://doi.org/10.1016/j.vgie.2023.04.003
Ponte A, Mascarenhas‑Saraiva M, Freitas D, Cerqueira Á, Magalhães J. Endoscopic resection of large gastrointestinal lipomas: loop-and-let-go technique with some twists. Gastroenterología y Hepatología. 2016;40(7):465-7. DOI: https://doi.org/10.1016/j.gastrohep.2016.06.001
Geraci G, Di Vita M, Lunetta M, Cottone M, Giacalone A, Licata A. Endoscopic resection of a large colonic lipoma: case report and review of literature. Case Rep Gastroenterol. 2010;4(1):6-11. DOI: https://doi.org/10.1159/000260053
Schopis M, Yang J. Endoscopic treatment of intussusception from massive colonic lipomas via endoscopic mucosal resection: a case series. ACG Case Rep J. 2019;6(9):e00177. DOI: https://doi.org/10.14309/crj.0000000000000177
Tsiaousidou A, Dimitrakopoulos I, Tsiaousidou E, Paroutoglou G, Skandalakis P, Karamanolis G. Giant transmural lipoma of the sigmoid colon. Hippokratia. 2012;16(3):278-81.
Lin JC, Liu Q, Lin Y, Hou X, Wang W. A case of a large colonic lipoma resected by endoscopic submucosal dissection: a long-term endoscopic observation. Adv Dig Med. 2017;4(3):114-6. DOI: https://doi.org/10.1002/aid2.12114
Panagiotakis GI, Manouras A, Antonakis PT, Kesisoglou I, Zografos GN. Laparoscopic resection of a sigmoid colon lipoma in a young female patient: a case report and review of the literature. Oncol Lett. 2017;13(3):1303-6. DOI: https://doi.org/10.3892/ol.2017.5594