Prevalence of gallbladder pathology: a four-year experience at a secondary care hospital in Mexico city
DOI:
https://doi.org/10.18203/2349-2902.isj20252917Keywords:
Cholecystitis, Gallbladder pathology, Laparoscopic cholecystectomy, PrevalenceAbstract
Background: Biliary tract diseases represent a common cause of medical consultation and surgical intervention in Mexico, with a rising incidence. Elective cholecystectomy is among the most frequently performed surgical procedures in secondary care hospitals, reflecting the significant clinical burden of this pathology.
Methods: A retrospective, descriptive and observational study was conducted in a secondary care hospital, including 12,475 patients. Demographic data, diagnoses, types of surgical intervention and the conversion rate from laparoscopic to open cholecystectomy were analyzed.
Results: The prevalence of biliary disease in the study population was 7.79%. The conversion rate from laparoscopic to open surgery ranged from 2.6% to 18%, depending on the specific diagnosis and the surgical team's experience. Acute cholecystitis and pyocolecyst were identified as the main factors increasing technical difficulty due to severe inflammation and an elevated risk of biliary tract injury, leading to conversion to open surgery. These findings underscore the complexity involved in surgically managing certain biliary conditions.
Conclusions: The high prevalence of biliary pathology and the considerable conversion rate highlight the necessity for careful clinical and surgical evaluation, as well as the importance of experienced surgeons to optimize management and reduce complications.
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References
Sainz MC, Galindo RJ. Historia de la colecistectomía y evolución de la cirugía biliar. Revista Española de Enfermedades Digestivas. 2015;107(9): 515–20.
Birtwhistle RV, Sauerbrei EE. Ultrasonography in the diagnosis of gallbladder disease. Can Fam Physician. 1983;29:1621-5.
Institute for Health Metrics and Evaluation (IHME). Global Burden of Disease Study 2019 (GBD 2019) Results. Seattle (WA): IHME; 2020. Available at: http://ghdx.healthdata.org/gbd-results-tool. Accessed on 21 February 2025.
Kaminski DL, Deshpande YG, Thomas L, Qualy J, Blank W. Effect of oral ibuprofen on formation of prostaglandins E and F by human gallbladder muscle and mucosa. Dig Dis Sci. 1985;30(10):933-40. DOI: https://doi.org/10.1007/BF01308292
Li J, Jin X, Ren J, Li R, Du L, Gao Y, et al. Global burden of gallbladder and biliary diseases: A systematic analysis for the Global Burden of Disease Study 2019. J Gastroenterol Hepatol. 2022;37:1389-99. DOI: https://doi.org/10.1111/jgh.15859
Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: Cholelithiasis and cancer. Gut Liver. 2012;6:172-87. DOI: https://doi.org/10.5009/gnl.2012.6.2.172
Alcocer TR, Tort MA, Olvera HH, Ugalde VF, Hernández ZJ. Papel de la colecistectomía subtotal laparoscópica en colecistitis aguda complicada. Rev Mex Cir Endoscop. 2016;17:146-50.
Motta‑Ramírez GA, Gámez‑Sala R. Vesícula en porcelana y carcinoma de vesícula: correlación de diagnósticos por imagen y anatomopatológico. Anales Radiol Méx. 2011;10(2):106–11.
Lane J, Buck JL, Zeman RK. Primary Carcinoma of the gallblader: A pictorial essay. Radiographics. 1989;9(2):209-28. DOI: https://doi.org/10.1148/radiographics.9.2.2648501
Castillo JJ, Romo C, Ruiz J, Escrivá JF, Córdova VH. Cáncer de vesícula biliar como hallazgo histopatológico posterior a la colecistectomía. Prevalencia e incidencia en el Hospital Ángeles del Pedregal. Acta Médica Grupo Ángeles. 2010;8(3):140-7.
Randi G, Franceschi S, La Vecchia C. Gallbladder cancer worldwide: geo-graphical distribution and risk factors. Int J Cancer. 2006;118(7):1591-602. DOI: https://doi.org/10.1002/ijc.21683
Etala E. Cáncer de la vesícula biliar. Prensa Med. Argent. 1962;49:2283-99.
Castro FA, Koshiol J, Hsing AW. Biliary tract cancer incidence in the United States-Demographic and temporal variations by anatomic site. Int J Cancer. 2013;133:1664–71. DOI: https://doi.org/10.1002/ijc.28161
Hsing AW, Gao YT, Han TQ, Rashid A, Sakoda LC, Wang BS, et al. Gallstones and the risk of biliary tract cancer: a population-based study in China. Br J Cancer. 2007;97(11):1577-82. DOI: https://doi.org/10.1038/sj.bjc.6604047
Tazuma S, Kajiyama G. Carcinogenesis of malignant lesions of the gall bladder. The impact of chronic inflammation and gallstones. Langenbecks Arch. Surg. 2001;386:224–9. DOI: https://doi.org/10.1007/s004230100220
Sampliner RE, Bennett PH, Comess LJ, Rose FA, Bruch TA. Gallbladder disease in Pima Indians. Demonstration of high prevalence and early onset by cholecystography. N Engl J Med. 1970;283(25):1358-64. DOI: https://doi.org/10.1056/NEJM197012172832502
Stephen AE, Berger DL. Carcinoma in the porcelain gallbladder: a relationship revisited. Surgery. 2001;129:699–703. DOI: https://doi.org/10.1067/msy.2001.113888