Quality of life in total fundoplication surgery versus partial fundoplication in patients with gastroesophageal reflux disease

Eduardo Sánchez-Soriano; Itzel G. García-Félix; Samuel R. Gómez-Arenas

doi:10.18203/2349-2902.isj20252887

Authors

Eduardo Sánchez-Soriano Department of Surgery, High Specialty Medical Unit (UMAE) No. 25 IMSS, University of Monterrey (UDEM), Monterrey, Nuevo León, México
Itzel G. García-Félix Department of Surgery, High Specialty Medical Unit (UMAE) No. 25 IMSS, University of Monterrey (UDEM), Monterrey, Nuevo León, México
Samuel R. Gómez-Arenas Department of Surgery, High Specialty Medical Unit (UMAE) No. 25 IMSS, Monterrey, Nuevo León, México

DOI:

https://doi.org/10.18203/2349-2902.isj20252887

Keywords:

Reflux, GERD, Anti-reflux surgery, Esophagitis, Fundoplication

Abstract

Background: Gastroesophageal reflux disease (GERD) is a chronic disease with a prevalence of 20%, which has increased in recent years with complications such as Barrett's esophagus and risk of esophageal adenocarcinoma. Therefore, its medical and surgical treatment is crucial for the prognosis.

Methods: A retrospective cohort study of quality of life using the GERD questionnaire (GERDQ) was performed in patients with GERD who received surgical treatment with one-year postoperative follow-up at a tertiary care hospital in 2023. Patients were divided into two groups based on treatment: total fundoplication (group A) and partial fundoplication (group B). Statistical analysis included percentages, means, standard deviations, and group comparisons using the Chi-square test.

Results: Of the 35 patients, the mean age was 53.71±11.26 years, more frequent in women (54.30%). Typical symptoms were presented in 85.70% of cases, with persistence of these in 68.60%, indicating surgery, with symptoms lasting 122±68.88 days. The most frequent comorbidities were obesity and diabetes (22.90%). 54.30% underwent total fundoplication (group A) and 45.70% underwent partial fundoplication (group B). A low probability of presenting GERD after surgery was 78.90% in group A versus 75% in group B.

Conclusions: The quality of life is good in patients with GERD after surgical treatment, both with total fundoplication and partial fundoplication, obtaining a low probability of presenting GERD in both surgeries with the GERDQ questionnaire, with similar percentages of 78.90% versus 75%.

Metrics

Metrics Loading ...

References

Townsend C, Evers M, Beauchamp D, Esófago MK. Tratado de Cirugía: fundamentos biológicos de la práctica quirúrgica moderna. 21st Edition. España: Elsevier. 2022;1030-4.

Brunicardi F, Andersen D, Bilfar T, Dunn D, Hunter J, Kao L, et al. Esófago y hernia diafragmática. In: Jobe B, Hunter J, Watson D. Schwartz. Principios de Cirugía. 11th edition. México DF: McGraw Hill. 2020;964-74.

Díaz de Liaño A, Yárnoz C, Garde C, Flores L, Artajona A, Romeo I, et al. Calidad de vida después de la funduplicatura laparoscópica para la enfermedad por reflujo gastroesofágico. Cir Esp. 2005;77(1):31-5. DOI: https://doi.org/10.1016/S0009-739X(05)70800-9

Moral M, Reoyo P, León M, Paloma L, Rodríguez S, Seco G. Fundoplicatura de Nissen laparoscópica, resultados y factores pronósticos. Rev Gastroenterol Mex. 2011;77(1):15-25.

Maret-Ouda J, Markar SR, Lagergren J. Gastroesophageal Reflux Disease: A Review. JAMA. 2020;324(24):2536-47. DOI: https://doi.org/10.1001/jama.2020.21360

Carrasquer A, Targarona E, Marinello F, Batlle X, Trias M. Resultados de la funduplicatura laparoscópica en el tratamiento de los síntomas extradigestivos del reflujo gastroesofágico. Cir Esp. 2012;90(4):238-42. DOI: https://doi.org/10.1016/j.ciresp.2011.12.008

Gomez X, Flores J, Elizalde A, Guarneros J, Cervera A, Ochoa R, et al. Resultados a largo plazo entre dos técnicas laparoscópicas antirreflujo. Rev AMCE. 2004;5(3):121-6.

Alemanno G, Bottari A, Giordano A, Prosperi P. Long-terms results in terms of QoL after laparoscopic Nissen fundoplication: a literature review. Laparosc Surg. 2021;5(9):92-4. DOI: https://doi.org/10.21037/ls-20-64

Roman S, Guadagnoli L, Hastier A, Becam E, Craven M, Napoléon M, et al. Validation of the French version of the esophageal hypervigilance and anxiety scale. Clin Res Hepatol Gastroenterol. 2021;45(2):101672. DOI: https://doi.org/10.1016/j.clinre.2021.101672

Contreras R, Sánchez O, Ángeles E. Comparison of the Carlsson-Dent and GERD-Q questionnaires for gastroesophageal reflux disease symptom detection in a general population. Rev Gastroenterol Mex. 2017;82(1):19-25. DOI: https://doi.org/10.1016/j.rgmxen.2016.12.003

Suzuki H, Matsuzaki J, Okada S, Hirata K, Fukuhara S, Hibi T. Validation of the GerdQ questionnaire for the management of gastro-oesophageal reflux disease in Japan. United European Gastroenterol J. 2013;1(3):175-83. DOI: https://doi.org/10.1177/2050640613485238

Bai Y, Du Y, Zou D, Jin Z, Zhan X, Li ZS, et al. Chinese GerdQ Research Group. Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real-world practice: a national multicenter survey on 8065 patients. J Gastroenterol Hepatol. 2013;28(4):626-31. DOI: https://doi.org/10.1111/jgh.12125

Kumar A, Raja K, Kumar S, Quasimuddin N, Rizwan A. Quality of Life in Gastroesophageal Reflux Disease Three Months After Laparoscopic Nissen's Fundoplication. Cureus. 2020;12(9):e10674. DOI: https://doi.org/10.7759/cureus.10674

Paranyak M, Patel R. A prospective randomized trial on laparoscopic total vs partial fundoplication in patients with atypical symptoms of gastroesophageal reflux disease. Langenbecks Arch Surg. 2023;408(1):269. DOI: https://doi.org/10.1007/s00423-023-03013-0

Dowgiałło-Gornowicz N, Kacperczyk J, Masiewicz A, Lech P, Saluk S, Osowiecka K, et al. Patient Satisfaction after Laparoscopic Nissen Fundoplication-Long-Term Outcomes of Single-Center Study. J Clin Med. 2021;10(24):5924. DOI: https://doi.org/10.3390/jcm10245924