Fascia lata: utilization and applications in dental therapy: a comprehensive review
DOI:
https://doi.org/10.18203/2349-2902.isj20251414Keywords:
Odontology, Fascia lata, Tissue transplantation, Regenerative medicine, Periodontal regenerationAbstract
Fascia lata has been identified as an alternative biomaterial in dentistry for tissue regeneration and transplantation. Its efficacy has been demonstrated in alveolar ridge reconstruction, management of gingival recessions, and guided bone regeneration. These applications are attributed to its inherent elasticity, biocompatibility, and the relative ease of donor tissue procurement, positioning it as a viable substitute for autologous connective tissue grafts. Compositional analyses reveal the presence of collagen, hyaluronic acid, fibroblasts, and telocytes-cells integral to tissue repair and regeneration. Two graft modalities exist: autografts and allografts, both subjected to lyophilization and gamma irradiation to mitigate immunogenic responses. Compared to palatal connective tissue grafts, fascia lata grafts exhibit reduced postoperative morbidity by limiting surgical intervention to a single site. Furthermore, its function as a biological membrane promotes mesenchymal cell differentiation into osteoblasts, thereby enhancing osteoinductive capacity. Notwithstanding these benefits, residual genetic material persists in allografts post-processing. Given these attributes, fascia lata represents a promising candidate for advancing periodontal regenerative therapies.
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References
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