A prospective application of LRINEC score in necrotising soft tissue infections
DOI:
https://doi.org/10.18203/2349-2902.isj20251427Keywords:
Cellulitis, CRP, LRINEC score, Necrotising soft tissue infectionAbstract
Background: Necrotising soft tissue infections are hastily progressing skin and soft tissue infections associated with necrosis of the dermis, subcutaneous tissue, superficial fascia, deep fascia or muscle. This includes a variety of conditions, such as Fournier’s gangrene affecting the perineum and genitalia, Meleney streptococcal gangrene and clostridial myonecrosis.
Methods: Prospective observational study. Patients presenting to hospital with clinical features of cellulitis will be included in the study. Patients and their caretakers will be explained the procedure and written consent obtained. All the patients will be investigated and LRINEC score measured.
Results: A total of 119 cases were included in the study of which 17 cases were necrotising soft tissue infections and 102 cases were diagnosed with cellulitis with no systemic complications.
Conclusions: In conclusion, the LRINEC score is a valuable tool for diagnosing necrotizing fasciitis. Its high sensitivity and specificity make it an ideal tool for clinicians to identify patients at high risk of this severe infection.
Metrics
References
Liu V, Escobar GJ, Greene JD. Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA. 2014;312:90–2. DOI: https://doi.org/10.1001/jama.2014.5804
Ban KA, Minei JP, Laronga C. American College of Surgeons and Surgical Infection Society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2017;224:59–74. DOI: https://doi.org/10.1016/j.jamcollsurg.2016.10.029
Wong CH, Chang HC, Pasupathy S. Necrotizing fasciitis: clinical presentation, microbiology and determinants of mortality. J Bone Joint Surg Am. 2003;85:1454–60. DOI: https://doi.org/10.2106/00004623-200308000-00005
Fernando SM, Tran A, Cheng W. Necrotizing soft tissue infection: diagnostic accuracy of physical examination, imaging and LRINEC score: a systematic review and metaanalysis. Ann Surg. 2019;269:58–65. DOI: https://doi.org/10.1097/SLA.0000000000002774
Martinez M, Peponis T, Hage A. The role of computed tomography in the diagnosis of necrotizing soft tissue infections. World J Surg. 2018;42:82–7. DOI: https://doi.org/10.1007/s00268-017-4145-x
Sroczyński M, Sebastian M, Rudnicki J, Sebastian A, Agrawal AK. Complex approach to the treatment of Fournier’s gangrene. Adv Clin Exp Med. 2013;22:131–5.
Ord R, Coletti D. Cervico-facial necrotizing fasciitis. Oral Dis. 2009;15:133–41. DOI: https://doi.org/10.1111/j.1601-0825.2008.01496.x
Huang WS, Hsieh SC, Hsieh CS, Schoung JY, Huang T. Use of vacuum-assisted wound closure to manage limb wounds in patients suffering from acute necrotizing fasciitis. Asian J Surg. 2006;29:135–9. DOI: https://doi.org/10.1016/S1015-9584(09)60072-5
Kao LS, Lew DF, Arab SN. Local variations in the epidemiology, microbiology and outcome of necrotizing soft-tissue infections: a multi-center study. Am J Surg. 2011;202(2):139-45. DOI: https://doi.org/10.1016/j.amjsurg.2010.07.041
Sultan HY, Boyle AA, Sheppard N. Necrotising fasciitis. BMJ. 2012;345:4274–9. DOI: https://doi.org/10.1136/bmj.e4274
Hoatian Woo. a nested case control study on Modified Laboratory Risk Indicator for Necrotizing Fasciitis (m-LRINEC) Score System in Diagnosing Necrotizing Fasciitis. Infection and Drug Resistance 2021:14 2105–12. DOI: https://doi.org/10.2147/IDR.S313321
Ma WG, Zheng J, Sun LZ, Elefteriades JA. Open stented grafts for frozen elephant trunk technique: technical aspects and current outcomes. Aorta. 2015;3(04):122-35. DOI: https://doi.org/10.12945/j.aorta.2015.14.062
Downloads
Published
How to Cite
Issue
Section
