Ileo-colic intussusception in an adolescent secondary to high-grade B-cell (Burkitt’s) lymphoma: a case report and literature review

Authors

  • Supreet Kumar Department of Surgical Gastroenterology and GI Oncology, Indraprastha Apollo Hospital, New Delhi, India
  • Aishwarya S. Bhalerao Department of Surgical Gastroenterology and GI Oncology, Indraprastha Apollo Hospital, New Delhi, India
  • Suryalok P. Shah Department of Surgical Gastroenterology and GI Oncology, Indraprastha Apollo Hospital, New Delhi, India
  • Alok K. Pandey Department of Surgical Gastroenterology and GI Oncology, Indraprastha Apollo Hospital, New Delhi, India
  • Vivek Tandon Department of Surgical Gastroenterology and GI Oncology, Indraprastha Apollo Hospital, New Delhi, India
  • Deepak Govil Department of Surgical Gastroenterology and GI Oncology, Indraprastha Apollo Hospital, New Delhi, India

DOI:

https://doi.org/10.18203/2349-2902.isj20251185

Keywords:

Intussusception, Ileo-colic, Burkitt’s lymphoma, High-grade B-cell lymphoma, Immunohistochemistry

Abstract

Intussusception in older children and adolescents is relatively uncommon and is frequently associated with a pathological lead point. High-grade B-cell lymphomas (e.g., Burkitt lymphoma) may involve the abdomen and precipitate intussusception. A 16-year-old male presented with a two-week history of intermittent upper abdominal pain, melena, and symptomatic anemia. Contrast-enhanced computed tomography (CECT) demonstrated ileo-colic intussusception. Exploratory laparotomy revealed a polypoidal mass in the ascending colon acting as the lead point, necessitating a right hemicolectomy. Histopathological and immunohistochemical analyses confirmed high-grade B-cell lymphoma consistent with Burkitt lymphoma. The patient’s postoperative course was uneventful, and he was referred for chemotherapy. This case underscores the importance of considering Burkitt lymphoma in adolescent patients with intussusception. Prompt surgical intervention, definitive histopathological confirmation, and timely initiation of chemotherapy are critical to optimizing patient outcomes.

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References

Lehnert T, et al. Intussusception in adults: clinical presentation, diagnosis, and treatment. Int J Colorectal Dis. 2010;25(2):131-6.

Park JH, et al. The role of imaging in adult intussusception. AJR Am J Roentgenol. 2015;201(1):W1-8.

Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, et al. Burkitt's lymphoma. Lancet. 2012;379(9822):1234-44. DOI: https://doi.org/10.1016/S0140-6736(11)61177-X

Kelly K, et al. Pediatric non-Hodgkin lymphomas: diagnosis and treatment. Pediatr Clin North Am. 2015;62(1):139-55. DOI: https://doi.org/10.1016/j.pcl.2014.09.010

Magrath I. Epidemiology and pathophysiology of Burkitt’s lymphoma. Br J Haematol. 2012;156(6):693-703. DOI: https://doi.org/10.1111/j.1365-2141.2011.08877.x

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Published

2025-04-25

How to Cite

Kumar, S., Bhalerao, A. S., Shah, S. P., Pandey, A. K., Tandon, V., & Govil, D. (2025). Ileo-colic intussusception in an adolescent secondary to high-grade B-cell (Burkitt’s) lymphoma: a case report and literature review. International Surgery Journal, 12(5), 825–827. https://doi.org/10.18203/2349-2902.isj20251185

Issue

Section

Case Reports