The influence of diabetes mellitus on acute renal damage following coronary artery bypass graft surgery

Manjurul Hasan; Mohammad Mozammal Haque; M. Faysal Ahmed; Samsun Nahar; Syeda Najiba Hossain; Sirajum Munira

doi:10.18203/2349-2902.isj20250808

Authors

Manjurul Hasan Department of Vascular Surgery, Dhaka Medical College, Dhaka, Bangladesh
Mohammad Mozammal Haque Department of Surgery, OSD, Director General Health Services, Mohakhali, Dhaka, Bangladesh
M. Faysal Ahmed OSD, Director General Health Services, Mohakhali, Dhaka, Bangladesh
Samsun Nahar Department of Biochemistry, Bashundhara Ad-din Medical College and Hospital, Dhaka, Bangladesh
Syeda Najiba Hossain OSD, Director General Health Services, Mohakhali, Dhaka, Bangladesh
Sirajum Munira National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2349-2902.isj20250808

Keywords:

Diabetes Mellitus, Acute kidney injury, Coronary artery bypass grafting

Abstract

Background: DM is a known risk factor for developing postoperative acute kidney injury (AKI) after Coronary Artery Bypass Grafting (CABG). Postoperative AKI is associated with increased short- and long-term morbidity and mortality. This study aims to comprehensively evaluate the impact of diabetes mellitus on the occurrence and severity of AKI following CABG.

Methods: This comparative cross-sectional study was carried out in the department of cardiac surgery, national institute of cardiovascular diseases (NICVD) on a total of 60 patients undergoing CABG. Postoperative serum creatinine was measured at 24 hours, 48 hours and 72 hours after surgery. Group A included 30 patients who were diabetic and Group B included 30 patients who were non-diabetic. Statistical analysis was performed using statistical package for social sciences (SPSS). A p value<0.05 was considered statistically significant.

Results: During the observation period overall, 16 (26.67%) out of 60 patients developed postoperative AKI with varying severity. Among them, 12 patients were from diabetic group and only 4 patients belonged to non-diabetic group (40% vs. 13.33%, p<0.020). Consequently, duration of ICU stays (7.87±4.98.12 vs 4.13±2.65 days, p<0.001) and length of postoperative hospital stay (7.88±2.92 vs 13.0±4.95 days, p<0.001) were also found to be significantly prolonged in group A patients.

Conclusion: The present study revealed that patients with diabetes mellitus were more susceptible to develop post CABG AKI in spite of having no pre-existing renal impairment.

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References

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