Ultra early cranial and spinal metastasis in a post-operative case of 4th ventricle medulloblastoma case: a case report
DOI:
https://doi.org/10.18203/2349-2902.isj20250586Keywords:
Medulloblastoma, Spinal metastasis, Leptomeningeal spreadAbstract
Medulloblastoma is a type of brain tumour that occurs primarily in children and is relatively rare in adults. It has a tendency to spread through the cerebrospinal fluid pathways and can metastasize to other parts of the body, including the bones. Osseous extra-neural metastasis is uncommon, but the radiologic findings are usually sclerotic, lytic, or mixed when it occurs. In this paper, we present a case of medulloblastoma metastasizing to the cervical, dorsal and lumbar spine as well as intracranial spread and describe the magnetic resonance appearance of the lesion and also emphasize the importance of recognizing the imaging findings of metastatic lesions in patients with a history of medulloblastoma.
Metrics
References
Abacioglu U, Uzel O, Sengoz M, Turkan S, Ober A. Medulloblastoma in adults: treatment results and prognostic factors. Int J Rad Oncol Biol Physics. 2002;54(3):855-60. DOI: https://doi.org/10.1016/S0360-3016(02)02986-3
Algra PR, Postma T, Van Groeningen CJ, Van der Valk P, Bloem JL, Valk J. MR imaging of skeletal metastases from medulloblastoma. Skeletal Radiol. 1992;21(7):425-30. DOI: https://doi.org/10.1007/BF00190984
Millard NE, De Braganca KC. Medulloblastoma. J Child Neurol. 2016;31(12):1341-53. DOI: https://doi.org/10.1177/0883073815600866
Riffaud L, Saikali S, Leray E, Hamlat A, Haegelen C, Vauleon E, et al. Survival and prognostic factors in a series of adults with medulloblastomas. J Neurosurg. 2009;111(3):478-87.
Childhood cancer by the ICCC. In: Howlader N, Noone AM, Krapcho M, editors. SEER Cancer Statistics Review, 1975-2009 (Vintage 2009 Populations). National Cancer Institute. 2012.
Smoll NR, Drummond KJ. The incidence of medulloblastomas and primitive neurectodermal tumours in adults and children. J Clin Neurosci. 2012;19(11):1541-4. DOI: https://doi.org/10.1016/j.jocn.2012.04.009
Riffaud L, Saikali S, Leray E, Hamlat A, Haegelen C, Vauleon E, et al. Survival and prognostic factors in a series of adults with medulloblastomas. J Neurosurg. 2009;111(3):478-87. DOI: https://doi.org/10.3171/2009.1.JNS081004
Franceschi E, Giannini C, Furtner J, Pajtler KW, Asioli S, Guzman R, et al. Adult Medulloblastoma: Updates on Current Management and Future Perspectives. Cancers (Basel). 2022;14(15):3708. DOI: https://doi.org/10.3390/cancers14153708
Franceschi E, Minichillo S, Mura A, Tosoni A, Mascarin M, Tomasello C, et al. Adjuvant chemotherapy in average-risk adult medulloblastoma patients improves survival: a long term study. BMC Cancer. 2020;20(1):755. DOI: https://doi.org/10.1186/s12885-020-07237-x
Franceschi E, Hofer S, Brandes AA, Frappaz D, Kortmann RD, Bromberg J, et al. EANO-EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. Lancet Oncol. 2019;20(12):e715-28. DOI: https://doi.org/10.1016/S1470-2045(19)30669-2