Short term outcomes of laparoscopic surgery after treatment of colorectal cancer

Authors

  • M. Abdus Salam Department of Surgical Oncology, National Institute of Cancer Research and Hospital, Dhaka, Bangladesh
  • M. Ekramul Haque Department of Genitourinary Surgical Oncology, National Institute of Cancer Research and Hospital, Dhaka, Bangladesh
  • Mithun Kumar Mallick Department of Genitourinary Surgical Oncology, National Institute of Cancer Research and Hospital, Dhaka, Bangladesh
  • M. Erfan Siddiq Anwer Khan Modern Medical College and Hospital, Dhaka, Bangladesh
  • Mizanur Rahman Department of Surgical Oncology, National Institute of Cancer Research and Hospital, Dhaka, Bangladesh
  • Mahmudul Hasan Masum Department of Surgical Oncology, National Institute of Cancer Research and Hospital, Dhaka, Bangladesh
  • Muhammed Najibul Islam Department of Surgery, Gonoshasthaya Samaj Vittik Medical College and Hospital, Dhaka, Bangladesh
  • Mohammed Ashrafur Rahman Department of Surgery, National Institute of Cancer Research and Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2349-2902.isj20243979

Keywords:

Laparoscopic surgery, Colorectal cancer, Postoperative complications, Bangladesh, Short-term outcomes

Abstract

Background: Colorectal cancer is a significant health concern globally and in Bangladesh. Laparoscopic surgery is increasingly used for its treatment due to its minimally invasive nature, but comprehensive data on its short-term outcomes and complications in the Bangladeshi population is limited.

Methods: This prospective observational study was conducted from September 2018 to October 2019 at the Department of Surgical Oncology, National Institute for Cancer Research and Hospital, Dhaka. Thirty-nine patients diagnosed with colorectal cancer and undergoing laparoscopic surgery were included. Data on demographics, clinical presentations, colonoscopy findings, operative details, and postoperative outcomes were collected and analyzed using SPSS for Windows, version 22.0.

Results: The study population consisted of 58.97% males and 41.03% females. The most common chief complaints were per-rectal bleeding (48.72%) and abdominal pain (17.95%). Colonoscopy findings revealed ulcer proliferative lesions in 64.10% of patients. The mean operation time was 159.36 minutes, and the mean approximate blood loss was 124.5 ml. The mean postoperative hospital stay was 4.56 days. Minor postoperative complications included urinary tract infections (30.77%) and perineum infections (15.38%), while major complications included surgery conversion (12.82%) and postoperative mortality (2.56%).

Conclusions: Laparoscopic surgery for colorectal cancer offers significant benefits, such as reduced operative time, lower blood loss, and shorter hospital stays. However, the incidence of postoperative complications remains a concern, highlighting the need for improved surgical techniques and postoperative care. Addressing these challenges is crucial for optimizing patient outcomes and enhancing the adoption of laparoscopic surgery in Bangladesh.

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References

GLOBOCAN U. New global cancer data. UICC. 2020;27:2022.

Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global patterns and trends in colorectal cancer incidence and mortality. Gut. 2017;66(4):683-91. DOI: https://doi.org/10.1136/gutjnl-2015-310912

Safiri S, Sepanlou SG, Ikuta KS, Bisignano C, Salimzadeh H, Delavari A, et al. The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet Gastroenterol Hepatol. 2019;4(12):913-33. DOI: https://doi.org/10.1016/S2468-1253(19)30345-0

Lewandowska A, Rudzki G, Lewandowski T, Stryjkowska-Góra A, Rudzki S. Risk Factors for the Diagnosis of Colorectal Cancer. Cancer Control. 2022;29:10732748211056692. DOI: https://doi.org/10.1177/10732748211056692

Chen K, Qiu JL, Zhang Y, Zhao YW. Meta analysis of risk factors for colorectal cancer. World J Gastroenterol. 2003;9(7):1598-600. DOI: https://doi.org/10.3748/wjg.v9.i7.1598

Hamilton W, Round A, Sharp D, Peters TJ. Clinical features of colorectal cancer before diagnosis: a population-based case-control study. Br J Cancer. 2005;93(4):399-405. DOI: https://doi.org/10.1038/sj.bjc.6602714

Kennedy RH, Francis EA, Wharton R, Blazeby JM, Quirke P, West NP, et al. Multicenter Randomized Controlled Trial of Conventional Versus Laparoscopic Surgery for Colorectal Cancer Within an Enhanced Recovery Programme: EnROL. JCO. 2014;32(17):1804-11. DOI: https://doi.org/10.1200/JCO.2013.54.3694

Greene FL. Laparoscopic management of colorectal cancer. CA: A Cancer J Clinicians. 1999;49(4):221-8. DOI: https://doi.org/10.3322/canjclin.49.4.221

Yamamoto S, Inomata M, Kitano S, Katayama H, Mizusawa J, Konishi F, et al. Short-term clinical outcomes from a randomized controlled trial to evaluate laparoscopic and open surgery for stage II-III colorectal cancer: Japan Clin Oncol Group study JCOG 0404 (NCT00147134). JCO. 2012;30(4_suppl):538-8. DOI: https://doi.org/10.1200/jco.2012.30.4_suppl.538

Fazio VW, López-Kostner F. Role of Laparoscopic Surgery for Treatment of Early Colorectal Carcinoma. World J Surg. 2000;24(9):1056-60. DOI: https://doi.org/10.1007/s002680010145

Bedirli A, Salman B, Yuksel O. Laparoscopic versus Open Surgery for Colorectal Cancer: A Retrospective Analysis of 163 Patients in a Single Institution. Minim Invasive Surg. 2014;2014:530314. DOI: https://doi.org/10.1155/2014/530314

Greenblatt DY, Rajamanickam V, Pugely AJ, Heise CP, Foley EF, Kennedy GD. Short-Term Outcomes after Laparoscopic-Assisted Proctectomy for Rectal Cancer: Results from the ACS NSQIP. J Am Coll Surg. 2011;212(5):844. DOI: https://doi.org/10.1016/j.jamcollsurg.2011.01.005

COLOR Study Group. Impact of hospital case volume on short-term outcome after laparoscopic operation for colonic cancer. Surg Endosc. 2005;19(5):687-92. DOI: https://doi.org/10.1007/s00464-004-8920-z

Islam A, Biswas T. Health System in Bangladesh: Challenges and Opportunities. Am J Health Res. 2014;2:366. DOI: https://doi.org/10.11648/j.ajhr.20140206.18

Wilkinson E, Aruparayil N, Gnanaraj J, Brown J, Jayne D. Barriers to training in laparoscopic surgery in low- and middle-income countries: A systematic review. Trop Doct. 2021;51(3):408-14. DOI: https://doi.org/10.1177/0049475521998186

Tsai YJ, Huang SC, Lin HH, Lin CC, Lan YT, Wang HS, et al. Differences in gene mutations according to gender among patients with colorectal cancer. World J Surg Oncol. 2018;16(1):128. DOI: https://doi.org/10.1186/s12957-018-1431-5

Leufkens AM, Van Duijnhoven FJB, Boshuizen HC, Siersema PD, Kunst AE, Mouw T, et al. Educational level and risk of colorectal cancer in EPIC with specific reference to tumor location. Int J Cancer. 2012;130(3):622-30. DOI: https://doi.org/10.1002/ijc.26030

Majumdar SR, Fletcher RH, Evans AT. How Does Colorectal Cancer Present? Symptoms, Duration, and Clues to Location. Official journal of the Am Coll Gastroenterol ACG. 1999;94(10):3039. DOI: https://doi.org/10.1111/j.1572-0241.1999.01454.x

Harrison OJ, Smart NJ, White P, Brigic A, Carlisle ER, Allison AS, et al. Operative Time and Outcome of Enhanced Recovery After Surgery After Laparoscopic Colorectal Surgery. JSLS. 2024;18(2):265-72. DOI: https://doi.org/10.4293/108680813X13753907291918

Saleh A, Ihedioha U, Babu B, Evans J, Kang P. Is estimated intra-operative blood loss a reliable predictor of surgical outcomes in laparoscopic colorectal cancer surgery? Scott Med J. 2016;61(3):167-70. DOI: https://doi.org/10.1177/0036933015597174

Xu Z rong, Chi P. Comparison of the incidence of postoperative complications following laparoscopic and open colorectal cancer resection. Zhonghua wei chang wai ke za zhi = Chinese J Gastrointestinal Surg. 2012;15 8:810-3.

Procacciante F, Flati D, Diamantini G, Angelakis K, Cerioli A, Gaj F, et al. Severe postoperative complications in colorectal surgery for cancer. Incidence related to the techniques employed: open versus laparoscopic colectomy. Chir Ital. 2008;60(3):329-36.

Schiphorst AHW, Verweij NM, Pronk A, Rinkes IHMB, Hamaker ME. Non-surgical complications after laparoscopic and open surgery for colorectal cancer − A systematic review of randomised controlled trials. Euro J Surg Oncol. 2015;41(9):1118-27. DOI: https://doi.org/10.1016/j.ejso.2015.04.007

Nowakowski M, Pisarska M, Rubinkiewicz M, Torbicz G, Gajewska N, Mizera M, et al. Postoperative complications are associated with worse survival after laparoscopic surgery for non-metastatic colorectal cancer - interim analysis of 3-year overall survival. Videosurgery Miniinv. 2018;13(3):326-32. DOI: https://doi.org/10.5114/wiitm.2018.76179

Ishihara S, Matsuda K, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, et al. Patient Factors Predisposing to Complications Following Laparoscopic Surgery for Colorectal Cancers. Surgical Laparoscopy Endoscopy Percutaneous Techniques. 2015;25(2):168. DOI: https://doi.org/10.1097/SLE.0000000000000110

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Published

2024-12-28

How to Cite

Salam, M. A., Haque, M. E., Mallick, M. K., Siddiq, M. E., Rahman, M., Masum, M. H., Islam, M. N., & Rahman, M. A. (2024). Short term outcomes of laparoscopic surgery after treatment of colorectal cancer. International Surgery Journal, 12(1), 20–25. https://doi.org/10.18203/2349-2902.isj20243979

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Original Research Articles