Intra-operative use of arista (microporus polysaccharide haemosphere) in breast surgeries reduces post-operative risk of seroma formation: a case series and literature review

Authors

  • Tahmina Hakim Department of General Surgery, Unaccredited Trainee, Campbelltown Hospital, New South Wales, Australia
  • Caitlin Lim Department of General Surgery, Consultant of Breast and Endocrine Surgery, Campbelltown Hospital, New South Wales, Australia

DOI:

https://doi.org/10.18203/2349-2902.isj20252684

Keywords:

Arista, Breast surgery, Seroma, Post-operative complications

Abstract

The risk of seroma formation is a very common post-operative complication in breast surgeries like mastectomy, wide local excision, axillary dissection. The use of arista which is microporus polysaccharide haemosphere (MPH) can reduce the risks of seroma post-operatively. A case series study has been planned to be conducted using database of patient underwent breast surgeries requiring intra-operative Arista. Database of single surgeon’s 22 patients having breast surgeries in 1 year (2021-2022) were analysed. Out of 22 patients, majority of patients (20 patients) had no seroma with the use of Arista intra-operatively where variables accounted are patients age, type of surgery, amount of arista use, duration of drain, drain out-put, patient’s BMI, anticoagulation status, tissue histopathology, formation of seroma. The expected outcome would be use of MPH reduces risks of complications of breast surgeries like seroma and haematoma.

Metrics

Metrics Loading ...

References

Egeli T, Sevinç Aİ, Bora S, Yakut MC, Cevizci T, Canda T, et al. Microporous polysaccharide hemospheres and seroma formation after mastectomy and axillary dissection in rats. Balkan Med J. 2012;29(2):179-83. DOI: https://doi.org/10.5152/balkanmedj.2012.005

Bloom JA, Foroutanjazi S, Erlichman Z, Beqiraj Z, Jonczyk MM, Persing SM, et al. The use of hemostatic agents to decrease bleeding complications in breast cancer surgery. Am Surgeon. 2021;31348211029866. DOI: https://doi.org/10.1097/GOX.0000000000003744

Matsushita T, Masuda S, Inoue T. Early experience with combined use of two plant-based hemostatic agents. Ann Thoracic Surg. 2010;90(1):327-8. DOI: https://doi.org/10.1016/j.athoracsur.2009.08.067

Di Benedetto M, Gramellini M, Bona S, Ridolfi C, Capretti G, Montorsi M. The use of Arista AH as a local haemostatic agent in distal splenopancreatectomy: report of two cases. Drugs Context. 2024;13:2023-11-4. DOI: https://doi.org/10.7573/dic.2023-11-4

Lewis KM, Atlee H, Mannone A, Lin L, Goppelt A. Efficacy of hemostatic matrix and microporous polysaccharide hemospheres. J Surg Res. 2015;193(2):825-30. DOI: https://doi.org/10.1016/j.jss.2014.08.026

Emmez H, Tonge M, Tokgoz N, Durdag E, Gonul I, Cevıker N. Radiological and histopathological comparison of microporous polysaccharide hemospheres and oxidized regenerated cellulose in the rabbit brain: a study of efficacy and safety. Turk Neurosurgery. 2010;20(4):485-91. DOI: https://doi.org/10.5137/1019-5149.JTN.3300-10.2

Suarez-Kelly LP, Pasley WH, Clayton EJ, Povoski SP, Carson WE, Rudolph R. Effect of topical microporous polysaccharide hemospheres on the duration and amount of fluid drainage following mastectomy: a prospective randomized clinical trial. BMC Cancer. 2019;19(1):99. DOI: https://doi.org/10.1186/s12885-019-5293-1

LyBarger KS. Review of Evidence Supporting the Arista™ Absorbable Powder Hemostat. Med Devices (Auckl). 2024;17:173-88. DOI: https://doi.org/10.2147/MDER.S442944

Shinden Y, Nomoto Y, Nagata A, Eguchi Y, Yano H, Saho H, et al. Clinical effectiveness of microporous polysaccharide hemospheres in mastectomy for patients with breast cancer. Gland Surg. 2024;13(3):307-13. DOI: https://doi.org/10.21037/gs-23-297

Zhang R, Tan Y, Wang H. Preliminary evaluation on seroma prevention and treatment with transposition of tissue flaps and arista hemostatic powder. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2006;20(12):1220-3.

Selfridge JM, Sinner HF, Whiting J, Sun W, Mallory MA, Hoover SJ, et al. Effect of Microporous Polysaccharide Particles in Patients Undergoing Mastectomy. Clin Breast Cancer. 2022;22(8):e922-7. DOI: https://doi.org/10.1016/j.clbc.2022.07.015

Curcio F, Perri P, Piro P, Galassi S, Sole R, Trombino S, et al. Synthetic Haemostatic Sealants: Effectiveness, Safety, and In Vivo Applications. Pharmaceuticals (Basel). 2024;17(3):288. DOI: https://doi.org/10.3390/ph17030288

Mardani M, Eftekharian HR, Naseri M, Hosseini SMH, Mohammadi H, Danesteh H, et al. Hemostatic efficacy of composite polysaccharide powder (starch-chitosan) for emergency bleeding control: An animal model study. Surgery. 2022;172(3):1007-14. DOI: https://doi.org/10.1016/j.surg.2022.04.054

Downloads

Published

2025-08-26

How to Cite

Hakim, T., & Lim, C. (2025). Intra-operative use of arista (microporus polysaccharide haemosphere) in breast surgeries reduces post-operative risk of seroma formation: a case series and literature review. International Surgery Journal, 12(9), 1508–1511. https://doi.org/10.18203/2349-2902.isj20252684

Issue

Section

Case Series