Giant adolescent tubular adenoma of the breast mimicking giant fibroadenoma: a case report
DOI:
https://doi.org/10.18203/2349-2902.isj20242771Keywords:
Breast, Tubular adenoma, AdolescentAbstract
Tubular adenomas are a rare benign breast neoplasm, often clinically indistinguishable from fibroadenomas or phyllodes tumors. We present a case of the largest adolescent tubular adenoma reported in the literature, measuring 12.5 cm. Radiological evaluation and histopathological assessment of the core biopsy sample was consistent with a giant fibroadenoma. However, the final histopathological analysis of the excisional biopsy sample confirmed a tubular adenoma. This case highlights the clinical conundrum of reaching the definitive diagnosis in a patient with a tubular adenoma. A contemporary review of the clinical features, radiology, histopathology and management options for tubular adenoma of the breast was undertaken.
References
Alfehaid M, Hamad Alkharraz AA, Alsaeed H. Tubular Adenoma of the Breast Mimicking Fibroadenoma. Cureus. 2022;14(11):e31002.
Rodrigues RA, Azevedo CL, Djahjah MCR, and Pereira TSS. Tubular adenoma of the breast: radiological and ultrasound findings. Radiol Bras. 2018;51(5):341-2.
Miller MC, Johnson P, Kim S, Choi L. Tubular adenomas of the breast: a rare diagnosis. BMJ Case Rep. 2018;2018:bcr2018224631.
Sengupta S, Pal S, Biswas BK, Phukan JP, Sinha A, Sinha R. Preoperative Diagnosis of Tubular Adenoma of Breast-10 years of experience. N Am J Med Sci. 2014;6(5):219-23.
Joo GJ, Carter GJ, Berg WA. Tubular Adenoma of the Breast: Radiologic-Pathologic Correlation. J Breast Imaging. 2023;5(6):703-11.
Salemis NS, Gemenetzis G, Karagkiouzis G, Seretis C, Sapounas K, Tsantilas V, et al. Tubular adenoma of the breast: a rare presentation and review of the literature. J Clin Med Res 2012;4(1):64-7.
Shet TM, Rege JD. Aspiration cytology of tubular adenomas of the breast. An analysis of eight cases. Acta Cytol 1998;42(3):657-62.
Kumar N, Kapila K, Verma K. Characterization of tubular adenoma of breast--diagnostic problem in fine needle aspirates (FNAs). Cytopathology. 1998;9(5):301-7.
Mulvany N, Lowhagen T, Skoog L. Fine needle aspiration cytology of tubular adenoma of the breast. A report of two cases. Acta Cytol. 1994;38(6):961-4.
Ezer SS, Oguzkurt P, Ince E, Temiz A, Bolat FA, Hicsonmez A. Surgical treatment of the solid breast masses in female adolescents. J Pediatr Adolesc Gynecol. 2013;26 (1):31-5.
Hill RP, Miller Jr FN. Adenomas of the breast with case report of carcinomatous transformation in an adenoma. Cancer. 1954;7(2):318-24.
Saimura M, Anan K, Mitsuyama S, Ono M, Toyoshima S. Ductal carcinoma in situ arising in tubular adenoma of the breast. Breast Cancer. 2015;22(4):428-31.
Domoto H, Tsuda H, Miyakawa K, Shinoda A, Nanasawa T. Invasive ductal carcinoma associated with tubular adenoma of the breast. Pathol Int. 2002;52(3):244-8.
