A rare case of giant GIST: a case report and review of literature


  • Thiruvarul Muthukumarasamy Department of Surgical Gastroenterologist and GI Oncology, Thanjavur Medical College, Thanjavur, Tamil Nadu, India
  • Sumathi Ravikumar Department of General Surgery, Thanjavur Medical College, Thanjavur, Tamil Nadu, India
  • Vijay Kumar Department of General Surgery, Thanjavur Medical College, Thanjavur, Tamil Nadu, India
  • Venkatraman . Department of General Surgery, Thanjavur Medical College, Thanjavur, Tamil Nadu, India




Gastrointestinal stromal tumour, Imatinib, Sunitinib, CD34, CD117, DOG-1, Gastric GIST, PDGFR-A


Gastrointestinal stromal tumors are very rare tumors that constitute less than 1 percent of entire tumors of GIT. The case reported here is a 60 years male who came with complaints of mass in the abdomen and constipation. On examination, he had guarding. Radiological evaluation revealed a heterogenous mass behind the lesser sac displacing the solid organs posteriorly. And hence we proceeded with total gastrectomy with esophago-jejunostomy.  Histopathological examination revealed GIST arising from stomach which was positive for CD34 and C-KIT. Post-surgery patient was started on adjuvant imatinib therapy.


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Case Reports