Rectal perforation secondary to invasive cervical cancer presenting as perineal necrotizing fasciitis with subsequent hindquarter amputation: a case report

Matthew L. Basa; Andrew Riddell

doi:10.18203/2349-2902.isj20240339

Authors

Matthew L. Basa Department of General Surgery, Royal Brisbane and Women’s Hospital, Queensland Health, Brisbane, Queensland, Australia, School of Clinical Medicine, Royal Brisbane Clinical Unit, University of Queensland, Brisbane, Queensland, Australia
Andrew Riddell Department of General Surgery, Redcliffe Hospital, Queensland Health, Redcliffe, Queensland, Australia

DOI:

https://doi.org/10.18203/2349-2902.isj20240339

Keywords:

Necrotizing fasciitis, Rectal perforation, Cervical cancer

Abstract

Necrotizing fasciitis (NF) is a life-threatening soft tissue infection rarely associated with gynecological malignancies. We present a unique case of NF arising from a locally advanced cervical cancer eroding into the rectum, causing occult fecal spillage leading to severe infection and necessitating a hindquarter amputation. A 39-year-old woman presented with sepsis and a necrotic gluteal wound. Extensive debridement revealed "dishwater"-like discharge throughout the left leg fascial compartments, necessitating hindquarter amputation. Despite initial suspicion of a primary skin infection, further investigation revealed a posterolateral rectal perforation secondary to advanced cervical cancer, confirmed by biopsy and imaging. Microbiology identified Streptococcus constellatus, intermedius, and anginosus. This case highlights the atypical presentation of NF associated with advanced cervical cancer. High clinical suspicion and early surgical intervention are crucial for survival. This case expands the understanding of NF etiology and emphasizes the importance of considering rare causes, even in the absence of traditional risk factors.

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