Evaluation of unenhanced three-dimensional endoanal ultrasound scan in preoperative assessment of perianal sepsis
DOI:
https://doi.org/10.18203/2349-2902.isj20240569Keywords:
Endoanal ultrasound, Perianal fistula, Intersphincteric fistula, CorrelationAbstract
Background: Perianal sepsis which includes perianal fistula and abscess is a common clinical condition that requires thorough preoperative evaluation to decrease the recurrence rate and to plan relevant surgery according to the anatomy of the fistula. MRI and 3D EAUS are two important preoperative investigations that delineate the anatomy of simple and complex fistula tracts. Due to lower cost and easier use 3D EAUS is a safe and reliable first-line investigation in evaluating perianal abscess.
Methods: This is a retrospective and prospective analysis of patients with perianal sepsis who underwent pre-operative unenhanced 3D-EAUS in the departments of Colorectal surgery, Gastrointestinal surgery, and General surgery in our hospital. A B-K medical 2052 transducer was used for the study and the surgical assessment was done by multiple surgeons from multiple departments.
Results: A total of 255 patients were assessed. The accuracy for primary fistula tracts and internal opening was 83.53% and 88.62% respectively. The kappa coefficient of correlation was k=0.70 (substantial agreement) for the fistula tract and k=0.81 (near perfect agreement) for the internal opening. The sensitivity, and specificity of primary tracts and internal openings were calculated. Transphincteric fistulas were 57% in our study.
Conclusions: Unenhanced 3D EAUS is a reliable first-line investigation in preoperative evaluation of perianal fistula and abscess. Transphincteric fistula is the most common type of fistula. There is a high chance of correlation for the primary tract if a non-colorectal specialist performs the fistula surgery after 3D-EAUS without blinding.
References
Brillantino A, Iacobellis F, Di Sarno G, D'Aniello F, Izzo D, Paladino F, et al. Role of tridimensional endoanal ultrasound (3D-EAUS) in the preoperative assessment of perianal sepsis. Int J Colorectal Dis. 2015;30(4):535-42.
Kim Y, Park YJ. Three-dimensional endoanal ultrasonographic assessment of an anal fistula with and without H(2)O(2) enhancement. World J Gastroenterol. 2009;15(38):4810-5.
Brillantino A, Iacobellis F, Reginelli A, Monaco L, Sodano B, Tufano G, et al. Preoperative assessment of simple and complex anorectal fistulas: Tridimensional endoanal ultrasound? Magnetic resonance? Both? Radiol Med. 2019;124(5):339-49.
Sun MR, Smith MP, Kane RA. Current techniques in imaging of fistula in ano: three-dimensional endoanal ultrasound and magnetic resonance imaging. Semin Ultrasound CT MR. 2008;29(6):454-71.
Tsai SK, Lee TY, Mok MS. Gas embolism produced by hydrogen peroxide irrigation of an anal fistula during anesthesia. Anesthesiology. 1985;63(3):316-7.
Schwab C, Dilworth K. Gas embolism produced by hydrogen peroxide abscess irrigation in an infant. Anaesth Intens Care. 1999;27(4):418-20.
Lohsiriwat V, Prapasrivorakul S, Mongkhon-supphawan A. Hydrogen Peroxide-Induced Proctitis After Endoanal Ultrasound. Dis Colon Rectum. 2021; 64(2):e39.
Sullivan KM, Dean A, Soe MM. OpenEpi: A web-based epidemiologic and statistical calculator for public health. Public Health Rep. 2009;124:471-4.
McHugh ML. Interrater reliability: the kappa statistic. Biochem Med. 2012;22(3):276-82.
Nagendranath C, Saravanan MN, Sridhar C, Varughese M. Peroxide-enhanced endoanal ultrasound in preoperative assessment of complex fistula-in-ano. Tech Coloproctol. 2014;18(5):433-8.
Emile SH, Magdy A, Youssef M, Thabet W, Abdelnaby M, Omar W, et al. Utility of endoanal ultrasonography in assessment of primary and recurrent anal fistulas and for detection of associated anal sphincter defects. J Gastrointest Surg. 2017;21: 1879-87.
Garcés-Albir M, García-Botello SA, Espi A, Pla-Martí V, Martin-Arevalo J, Moro-Valdezate D, et al. Three-dimensional endoanal ultrasound for diagnosis of perianal fistulas: reliable and objective technique. World J Gastrointest Surg. 2016;8(7):513.
Almeida IS, Jayarajah U, Wickramasinghe DP, Samarasekera DN. Value of three-dimensional endoanal ultrasound scan (3D-EAUS) in preoperative assessment of fistula-in-ano. BMC Res Notes. 2019; 12(1):1-5.
West RL, Dwarkasing S, Felt-Bersma RJ, Schouten WR, Hop WC, Hussain SM, et al. Hydrogen peroxide-enhanced three-dimensional endoanal ultrasonography and endoanal magnetic resonance imaging in evaluating perianal fistulas: agreement and patient preference. Eur J Gastroenterol Hepatol. 2004; 16(12):1319-24.
Buchanan GN, Bartram CI, Williams AB, Halligan S, Cohen CR. Value of hydrogen peroxide enhancement of three-dimensional endoanal ultrasound in fistula-in-ano. Dis Colon Rectum. 2005;48:141-7.
Li J, Chen SN, Lin YY, Zhu ZM, Ye DL, Chen F, et al. Diagnostic Accuracy of Three-Dimensional Endoanal Ultrasound for Anal Fistula: A Systematic Review and Meta-analysis. Turk J Gastroenterol. 2021;32(11):913.
Lengyel AJ, Hurst NG, Williams JG. Pre-operative assessment of anal fistulas using endoanal ultrasound. Colorectal Dis. 2002;4(6):436-40.
Ratto C, Grillo E, Parello A, Costamagna G, Doglietto GB. Endoanal ultrasound-guided surgery for anal fistula. Endoscopy. 2005;37(08):722-8.
Jimenez M, Mandava N. Anorectal Fistula. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2022.