A report of a giant parathyroid adenoma

Authors

  • Ana Catarina M. Rodrigues Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal
  • Catarina Muller Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal
  • Carlos Moreira Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal
  • Duarte Gil Alves Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal
  • Sara Fernandes Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal
  • António Girão Caires Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal
  • Jorge Fernandes Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal
  • Carmo Caldeira Department of General Surgery, Hospital Dr. Nélio Mendonça, Funchal, Portugal

DOI:

https://doi.org/10.18203/2349-2902.isj20233934

Keywords:

Giant parathyroid adenoma, Hyperparathyroidism, Nephrolithiasis

Abstract

Giant parathyroid adenoma is a rare condition characterized by the presence of an abnormally large tumor in the parathyroid gland. A 62-year-old patient diagnosed with primary hyperparathyroidism and severe nephrolithiasis leading to nephrectomy. During workup for etiologic origin of hyperparathyroidism she was found to have a giant parathyroid adenoma with 7,8x3,6x4,3 cm estimated dimensions, located posteriorly to the trachea and extending to the thoracic inlet. She was then submitted to a Kocher cervicotomy and a partial superior sternotomy. The diagnosis is initially made throw laboratorial tests that reveal the elevated calcium and PTH levels. After diagnosis, imaging studies are essential to locate the gland in order to safely remove the entire associated adenoma. Management of giant adenoma is surgical with most patients achieving cure after the gland excision.

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References

Al-Hassan MS, Mekhaimar M, El Ansari W. Giant parathyroid adenoma: a case report and review of the literature. J Med Case Rep. 2019;13:332.

Bhan A, Athimulam S, Kumari P, Pal R, Bhadada SK, Cook BC, et al. Large parathyroid adenomas: Potential mechanisms to reconcile adenoma size and disease phenotype. Front Endocrinol. 2023;14: 1009516.

Ladan N, Michael L, Abberly LL, Nolan S. Giant parathyroid adenoma causing primary hyperparathyroidism. Otolaryngol Case Rep. 2023;29: 100555.

Houas J, Ghammam M, Chouchane L, Bellakhdher M, Dardouri T, Abdelkefi M. Acute presentation of giant parathyroid adenoma extending to the mediastinum: A case report. Int J Surg Case Rep. 2023;106:108282.

Shah S, Fujikawa P, Brand K, Munshi V, Patel K. Giant Parathyroid Adenoma: A Case Report. Cureus. 2023;15(1):e34140.

Zabielska B., Rzepakowska A: Revision of diagnostic guidelines for parathyroid adenoma based on case reports and a literature review. Pol Otorhino Rev. 2023;12(2):55-60.

Spanheimer PM, Stoltze AJ, Howe JR, Sugg SL, Lal G, Weigel RJ. Do giant parathyroid adenomas represent a distinct clinical entity?. Surgery. 2013; 154(4):714-19.

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Published

2023-12-27

How to Cite

Rodrigues, A. C. M., Muller, C., Moreira, C., Alves, D. G., Fernandes, S., Caires, A. G., Fernandes, J., & Caldeira, C. (2023). A report of a giant parathyroid adenoma. International Surgery Journal, 11(1), 132–134. https://doi.org/10.18203/2349-2902.isj20233934

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Section

Case Reports