Assessment of risk factors in patients undergoing difficult cholecystectomy: a cross-sectional study at a tertiary care hospital in Central India

Authors

  • Unmed Chandak Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India
  • Kapil Chauhan Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India
  • B. B. Gupta Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India
  • Arti Mitra Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India
  • Prasad Bansod Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India
  • Rohit Upadrashta Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India
  • Aditi Mundhada Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India

DOI:

https://doi.org/10.18203/2349-2902.isj20233924

Keywords:

LC, Gallstone disease, Difficult, Cholecystitis, Pancreatitis, Triangle of Calot‘s

Abstract

Background: Laparoscopic cholecystectomy (LC) is the operation of choice in the treatment of symptomatic gallstone disease. Most of the time, the levels of difficulties are hard to assume. The risk factors for difficult LC have not been adequately evaluated in Indian population, especially with respect to western Indian population. Thus, the present study was undertaken to assess the risk factors in patients undergoing difficult cholecystectomy.

Method: The study involved 100 adult patients with cholelithiasis admitted in the department of surgery for cholecystectomy over a period of 2 years from Nov 2020 to Dec 2022. Preoperatively, patients were evaluated for risk factors including age, gender, BMI, history of sickle cell disease, previous abdominal surgery, presence of pericholecystic collection, gall bladder thickness, impacted calculi, adhesions in triangle of Calot‘s, and previous hospitalization for acute cholecystitis and acute pancreatitis. These factors were assessed to predict difficult LC.

Results: Majority of laparoscopic procedures were easy (65%), while remaining were difficult (35%). Difficult cholecystectomy was significantly associated with age ≥50 years (p=0.016), male gender (p=0.031), BMI ≥25 kg/m2 (p<0.0001), sickle cell disease (p=0.030), previous abdominal surgery (p=0.004), pericholecystic collection (p=0.017), gall bladder thickness ≥4 mm (p=0.007), adhesion in triangle of Calot‘s (p<0.0001), impacted calculi (p=0.036), previous hospitalization for acute cholecystitis and acute pancreatitis (p<0.0001) and diabetes mellitus (p<0.0001). The conversion rate was 2%.

Conclusions: An awareness about reliable predictors for difficult LC would be helpful for an appropriate treatment plan and application of the resources to anticipate difficult LC. However, further studies with larger sample size are required to confirm the findings.

 

Metrics

Metrics Loading ...

References

Litynski GS. Highlights in the History of Laparoscopy. Frankfurt, Germany: Barbara Bernert Verlag. 1996;165-8.

Bansod AN, Patil IG, Awachar NS, Umalkar RK, Wankhede AM, Jadhav VK. A study of preoperative factors predicting a difficult laparoscopic cholecystectomy. Int Surg J. 2022;9(5):972-6.

Reynolds W Jr. The first laparoscopic cholecystectomy. JSLS. 2001;5(1):89-94.

Khetan AK, Yeola M. Preoperative prediction of difficult laparoscopic cholecystectomy using a scoring system. Int Surg J. 2017;4:3388-91.

Bourgouin S, Mancini J, Monchal T, Calvary R, Bordes J et al. How to predict difficult laparoscopic cholecystectomy? Proposal for a simple preoperative scoring system. Am J Surg. 2016;212(5):873-81.

Zaineb T, Hassaan A, Hajirah K, Hassan M, Syeda Ameera N et al., Preoperative Factors Associated with Difficult Laparoscopic Cholecystectomy. Biomed J Sci Tech Res. 2021;33(1):25531-6.

Bhandari TR, Khan SA, Jha JL. Prediction of difficult laparoscopic cholecystectomy: An observational study. Ann Med Surg (Lond). 2021;72:103060.

Ramírez-Giraldo C, Alvarado-Valenzuela K, Isaza-Restrepo A et al. Predicting the difficult laparoscopic cholecystectomy based on a preoperative scale. Updates Surg. 2022;74:969-77.

Zisman A, Gold-Deutch R, Zisman E, Negri M, Halpern Z, Lin G et al. Is male gender a risk factor for conversion of laparoscopic into open cholecystectomy? Surg Endosc. 1996;10(9):892-4.

Schafer M, Krahenbuhl L, Buchler MW. Predictive factors for the type of surgery in acute cholecystitis. Am J Surg. 2001;182:291-7.

Rosen M, Brody F, Ponsky J. Predictive factors for conversion of laparoscopic cholecystectomy. Am J Surg. 2002;184(3):254-8.

Simopoulos C, Polychronidis A, Botaitis S, Perente S, Pitiakoudis M. Laparoscopic cholecystectomy in obese patients. Obes Surg. 2005;15(2):243-6.

Bunkar SK, Yadav S, Singh A, Agarwal K, Sharma P, Sharma AC. Factors predicting difficult laparoscopic cholecystectomy: a single institution experience. Int Surg J. 2017;4:1743-7.

Ghadhban BR. Assessment of the difficulties in laparoscopic cholecystectomy among patients at Baghdad province. Ann Med Surg (Lond). 2019;41:16-19.

Adisa AO, Adedeji TA, Bolarinwa RA, Owojuyigbe TO, Jeje OA, Glasbey J et al. The Inflammatory Response to Surgery in Sickle Cell Disease Patients Undergoing Cholecystectomy. JSLS. 2019;23(2):e2019.00027.

Hussain A. Difficult laparoscopic cholecystectomy: current evidence and strategies of management. Surg Laparosc Endosc Percutan Tech. 2011;21(4):211-7.

Agrawal N, Singh S, Khichy S. Preoperative prediction of difficult laparoscopic cholecystectomy: A scoring method. Niger J Surg. 2015;21:130-3.

Botaitis S, Pitiakoudis M, Perente S, Tripsianis G, Polychronidis A, Simopoulos C. Laparoscopic cholecystectomy in acute cholecystitis: an analysis of the risk factors. S Afr J Surg. 2012;50(3):62-8.

Dhanke PS, Ugane SP. Factors predicting difficult laparoscopic cholecystectomy: a single-institution experience. Int J Stud Res. 2014;4(1):3-7.

Lipman JM, Claridge JA, Haridas M, Matthew DM, David CY, Kevin LG et al. Preoperative findings predict conversion from laparoscopic to open cholecystectomy. Surgery. 2007;142(4):556-63.

Fried GM, Barkun JS, Sigman HH, Joseph L, Clas D, Garzon J, et al. Factors determining conversion to laparotomy in patients undergoing laparoscopic cholecystectomy. Am J Surg 1994;167:35-9.

Lal P, Agarwal PN, Malik VK, Chakravarti AL. A difficult laparoscopic cholecystectomy that requires conversion to open procedure can be predicted by preoperative ultrasonography. JSLS. 2002;6:59-63.

Gupta N, Ranjan G, Arora MP, Goswami B, Chaudhary P, Kapur A et al. Validation of a scoring system to predict difficult laparoscopic cholecystectomy. Int J Surg. 2013;11(9):1002-6.

Sugrue M, Coccolini F, Bucholc M, Johnston A. Contributors from WSES. Intraoperative gallbladder scoring predicts conversion of laparoscopic to open cholecystectomy: a WSES prospective collaborative study. World J Emerg Surg. 2019;14:12.

Goyal P, Muthuraman S, Sharma S. Simple and Reliable Scoring System to Predict Difficult Laparoscopic Cholecystectomy Preoperatively. World J Lap Surg. 2021;14(1):34-8.

Livingston EH, Rege RV. A nationwide study of conversion from laparoscopic to open cholecystectomy. Am J Surg. 2004;188(3):205-11.

Singh K, Ohri A. Difficult laparoscopic cholecystectomy: A large series from north India. Indian J Surg. 2006;68:205-8.

Sippey M, Grzybowski M, Manwaring ML, Kasten KR, Chapman WH, Pofahl WE et al. Acute cholecystitis: risk factors for conversion to an open procedure. J Surgical Res. 2015;199(2):357-61.

Johansson M, Thune A, Nelvin L, Stiernstam M, Westman B, Lundell L. Randomized clinical trial of open versus laparoscopic cholecystectomy in the treatment of acute cholecystitis. Br J Surg. 2005;92(1):44-9.

Terho PM, Leppäniemi AK, Mentula PJ. Laparoscopic cholecystectomy for acute calculous cholecystitis: a retrospective study assessing risk factors for conversion and complications. World J Emerg Surg. 2016;11:54.

Downloads

Published

2023-12-27

How to Cite

Chandak, U., Chauhan, K., Gupta, B. B., Mitra, A., Bansod, P., Upadrashta, R., & Mundhada, A. (2023). Assessment of risk factors in patients undergoing difficult cholecystectomy: a cross-sectional study at a tertiary care hospital in Central India. International Surgery Journal, 11(1), 63–69. https://doi.org/10.18203/2349-2902.isj20233924

Issue

Section

Original Research Articles